Disease

Research scientist Bogdan Fedeles and postdoc Supawadee Chawanthayatham have discovered a mutational signature that reveals liver cell exposure to aflatoxin, a potent carcinogen.

Detecting mutations could lead to earlier liver cancer diagnosis

New technique can reveal exposure to aflatoxin, a potent carcinogen, before tumors develop.

March 27, 2017

A new paper from an MIT-led team demonstrates that Alaska can offer a significant foothold for Asian flu viruses, enabling them to enter North America.

Tracking the spread of bird flu

Asian flu strains can enter North America through Alaska, study finds.

March 17, 2017

A raindrop, splashing on a porous surface, can release thousands of aerosols, as captured here in high-speed imaging experiments.

A light rain can spread soil bacteria far and wide, study finds

Global precipitation may account for 1 to 25 percent of bacteria emitted from land.

March 7, 2017

After feeding C. elegans worms an equal mix of bacteria that express either red or green fluorescent protein, MIT researchers found that the microbial populations in the worms’ digestive tracts tend to become dominated by one or the other.

Microbiome diversity is influenced by chance encounters

Study finds a role for randomness in the composition of the gut’s microbe populations.

March 3, 2017

A new MIT transmitter that measures dopamine overcomes limitations of earlier transmitters, providing accurate readings for longer periods of time and covering more of the brain.

Precise technique tracks dopamine in the brain

New sensor could reveal the neurotransmitter’s role in learning and habit formation.

March 3, 2017

A team of MIT biological engineers has developed a method to measure levels of the iron-containing protein heme inside the malaria parasite. “One of our long-term goals is ultimately being able to tie insights from these studies back to thinking about drug discovery and targeting pathways that regulate heme,” says Jacquin Niles, an MIT associate professor of biological engineering.

Taking aim at a key malaria molecule

Measuring the parasite’s heme levels could help scientists develop better antimalarial drugs.

February 27, 2017

Eight student teams pitched novel inventions at last night’s MIT Sloan Healthcare Innovations Prize pitch competition. Rendever earned the $25,000 grand prize for creating a virtual-reality platform that gives the elderly the chance to explore the world virtually. The platform also provides cognitive therapy and tracks movement data to aid in early diagnosis of dementia.

Virtual-reality system for the elderly wins health care prize

Eight student teams pitched novel inventions at MIT Sloan Healthcare Innovations Prize competition.

February 24, 2017

How the U.S. can beat hepatitis C: Don’t buy the pills, buy the company

Pharma veteran and MIT visiting scientist Mark Trusheim advances a provocative solution to overcome treatment costs.

January 20, 2017

MIT engineers have shown that they can use short bursts of ultrasound to efficiently deliver RNA into cells.

RNA hitches a ride on ultrasound waves

Technique enables rapid delivery of RNA to treat colon inflammation.

January 20, 2017

“Understanding how our innate immune system works is important for thinking about the development of new ways to treat infectious disease,” says MIT associate professor of chemistry Elizabeth Nolan.

Exploring the tug-of-war over metals during infection

Chemist Elizabeth Nolan studies the battle between microbes and hosts for essential metals.

January 4, 2017

The star-shaped drug delivery device, held here by Giovanni Traverso, a Koch Institute research affiliate, can be folded inward and encased in a smooth capsule. Once ingested, the device delivers a full drug payload gradually over weeks or even months.

New capsule achieves long-term drug delivery

Technology could aid in elimination of malaria and treatment of many other diseases.

November 16, 2016

Common Sensing co-founders Richard Whalley (left) and James White

Data-driven diabetes management

Smart insulin-pen cap lets patients and doctors track dosage data to better manage treatment.

November 16, 2016

The TechCon conference, hosted by MIT and USAID's Higher Education Solutions Network from Nov. 10 - 12, convened researchers and innovators to collaborate on solving global issues.

At TechCon, science-based solutions for world issues

Innovators and researchers tackle global issues through actionable research and collaboration.

November 15, 2016

Four nucleotides, abbreviated A, C, G, and T, spell out DNA sequences that code for all of the proteins cells need. MIT researchers have now discovered another layer of control, mediated by transfer RNA, that helps cells to rapidly divert resources in emergency situations.

Cracking the code for dormant bacteria

Newly discovered genetic code controls bacterial survival during infections.

November 11, 2016

A team of researchers at MIT, the University of Brasilia, and the University of British Columbia has now engineered an antimicrobial peptide that can destroy many types of bacteria, including some that are resistant to most antibiotics.

Engineers design a new weapon against bacteria

Antimicrobial peptides can kill strains resistant to existing antibiotics.

November 2, 2016

MIT News | Massachusetts Institute of Technology

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