Biological engineering

By expanding brain tissue twice, researchers were able to obtain high-resolution images of neurons in the hippocampus.

High-resolution imaging with conventional microscopes

Tissue-expansion technique could allow scientists to map brain circuits.

April 17, 2017

MIT professors James Collins (left) and Feng Zhang are co-authors of a new paper reporting that an RNA-targeting CRISPR enzyme can be harnessed as a highly sensitive detector able to indicate the presence of as little as a single molecule of a target RNA or DNA.

Scientists unveil CRISPR-based diagnostic platform

New system adapts tool known for gene editing; to be used in rapid, inexpensive disease diagnosis.

April 13, 2017

Eleven from MIT elected to American Academy of Arts and Sciences for 2017

Prestigious honor society announces 228 new members this year.

April 12, 2017

Researchers have found a way to make tiny particles that can be injected into the body, where they emit short-wave infrared light. The advance may open up a new way of making detailed images of internal body structures such as fine networks of blood vessels.

Nanoparticles open new window for biological imaging

“Quantum dots” that emit infrared light enable highly detailed images of internal body structures.

April 10, 2017

Research scientist Bogdan Fedeles and postdoc Supawadee Chawanthayatham have discovered a mutational signature that reveals liver cell exposure to aflatoxin, a potent carcinogen.

Detecting mutations could lead to earlier liver cancer diagnosis

New technique can reveal exposure to aflatoxin, a potent carcinogen, before tumors develop.

March 27, 2017

A new paper from an MIT-led team demonstrates that Alaska can offer a significant foothold for Asian flu viruses, enabling them to enter North America.

Tracking the spread of bird flu

Asian flu strains can enter North America through Alaska, study finds.

March 17, 2017

Mild heating of graphene oxide sheets makes it possible to bond particular compounds to the sheets’ surface, a new study shows. These compounds in turn select and bond with specific molecules of interest, including DNA and proteins, or even whole cells. In this image the treated graphene oxide on the right is nearly twice as efficient at capturing cells as the untreated material on the left.

Graphene sheets capture cells efficiently

New method could enable pinpoint diagnostics on individual blood cells.

March 3, 2017

A team of MIT biological engineers has developed a method to measure levels of the iron-containing protein heme inside the malaria parasite. “One of our long-term goals is ultimately being able to tie insights from these studies back to thinking about drug discovery and targeting pathways that regulate heme,” says Jacquin Niles, an MIT associate professor of biological engineering.

Taking aim at a key malaria molecule

Measuring the parasite’s heme levels could help scientists develop better antimalarial drugs.

February 27, 2017

CEHS postdoc winners, from left to right: Yehuda Brody (2nd place), Supawadee Chawanthayatham (1st place), and Victor Hernandez-Gordillo and Annelien Zweemer (3rd-place tie).

Center for Environmental Health Sciences selects 2017 poster winners

Annual poster session showcases recent work on biological effects of exposure to environmental agents.

February 23, 2017

Charles Jennings, director of the McGovern Institute for Brain Research Neurotechnology program.

3Q: US patent office’s ruling on CRISPR

Charles Jennings of MIT’s McGovern Institute discusses the intellectual property dispute over the gene-editing technique.

February 22, 2017

Researchers have found that the hydrogel’s mostly watery environment helps keep nutrients and programmed bacteria alive and active. When the bacteria reacts to a certain chemical, the bacteria are programmed to light up, as seen on the left.

Living sensors at your fingertips

Cell-infused gloves and bandages light up when in contact with certain chemicals.

February 15, 2017

“The challenge is to engineer a system where we get enough growth to have a productive microbial ‘ chemical factory’ but not so much that we can’ t channel enough of the sugars into a pathway to make large quantities of our target molecules,”says Kristala Prather, an associate professor of chemical engineering at MIT.

Chemical engineers boost bacteria’s productivity

New technique improves yield of useful chemicals.

February 13, 2017

At StartMIT Innovation Night, innovators discuss their founders’ journeys and the impact they’ve made along the way.

StartMIT’s Innovation Night

Innovators from a range of fields discuss their pioneering work and their founders’ journey.

January 26, 2017

Kevin Kung, a Tata Fellow and PhD candidate in biological engineering, feeds rice husks into the torrefaction reactor in his lab at MIT. A thermochemical process will convert the biomass to a more energy-dense form, making it easier to transport and use as fuel.

Tapping the hidden value of farm waste

MIT researchers are developing mobile torrefaction technology that can convert biomass into clean-burning fuel, unlocking potential income for farmers.

January 25, 2017

“Diesel is the preferred fuel because of its high energy density and the high efficiency of the engines that run on diesel,” professor Gregory Stephanopoulos says. “The problem with diesel is that so far it is entirely made from fossil fuels.”

A step toward renewable diesel

Chemical engineers program yeast to convert plant sugars into oils.

January 16, 2017

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