Taking a moonshot at a rare childhood cancer
Team of researchers including MIT Professor Angela Koehler obtains $5.8 million grant to study fusion-positive alveolar rhabdomyosarcoma.
Technique identifies T cells primed for certain allergies or infections
Researchers develop a method to isolate and sequence the RNA of T cells that react to a specific target.
Nanoparticle orientation offers a way to enhance drug delivery
Coating particles with “right-handed” molecules could help them penetrate cancer cells more easily.
New synthesis method yields degradable polymers
Materials could be useful for delivering drugs or imaging agents in the body; may offer alternative to some industrial plastics.
Eric Alm and Peter Dedon receive NIH Transformative Research Award
Award will support interdisciplinary research on the role of the human microbiome in health and disease.
Biologists build proteins that avoid crosstalk with existing molecules
Engineered signaling pathways could offer a new way to build synthetic biology circuits.
Drug combination reverses hypersensitivity to noise
Findings in mice suggest targeting certain brain circuits could offer new ways to treat some neurological disorders.
Whitehead Institute team resolves structure of master growth regulator
New research reveals how mTORC1 docks at lysosomal surface.
Study reveals how mucus tames microbes
Specialized sugar molecules called glycans can disarm opportunistic pathogens and prevent infection.
New method visualizes groups of neurons as they compute
Fluorescent probe could allow scientists to watch circuits within the brain and link their activity to specific behaviors.
New capsule can orally deliver drugs that usually have to be injected
Coated pill carries microneedles that deliver insulin and other drugs to the lining of the small intestine.
Engineered viruses could fight drug resistance
By tweaking bacteriophage genomes, MIT team creates a new weapon to combat infection.
Technique can image individual proteins within synapses
Rapid imaging method could help reveal how conditions such as autism affect brain cells.
Perception of musical pitch varies across cultures
How people interpret musical notes depends on the types of music they have listened to, researchers find.
Using machine learning to estimate risk of cardiovascular death
CSAIL system uses a patient's ECG signal to estimate potential for cardiovascular death.