Study offers an explanation for why the APOE4 gene enhances Alzheimer’s risk
The gene variant disrupts lipid metabolism, but in cell experiments the effects were reversed by choline supplements.
Chemists boost boron’s utility
A strategy for preventing boron-containing compounds from breaking down could help medicinal chemists design new drugs.
Metabolic mutations help bacteria resist drug treatment
Study suggests forcing bacteria to burn more energy could make them more susceptible to antibiotics.
Toward a disease-sniffing device that rivals a dog’s nose
Trained dogs can detect cancer and other diseases by smell. A miniaturized detector can analyze trace molecules to mimic the process.
New surgery may enable better control of prosthetic limbs
Reconnecting muscle pairs during amputation gives patients more sensory feedback from the limb.
Machine-learning model helps determine protein structures
New technique reveals many possible conformations that a protein may take.
Our gut-brain connection
“Organs-on-a-chip” system sheds light on how bacteria in the human digestive tract may influence neurological diseases.
A high-resolution glimpse of gene expression in cells
Expanding tissue samples before sequencing allows researchers to pinpoint locations of RNA molecules.
Catching cancer in the act
Using CRISPR technology, researchers are tracking the lineage of individual cancer cells as they proliferate and metastasize in real-time.
Why cancer cells waste so much energy
MIT study sheds light on the longstanding question of why cancer cells get their energy from fermentation.
Can mammogram screening be more effective?
Study: Healthier women are more likely to follow age-based guidelines, leaving room for better-targeted testing.
“SCOUT” helps researchers find, quantify significant differences among organoids
Unbiased, high-throughput analysis pipeline improves utility of “minibrains” for understanding development and diseases such as Zika infection.
Sensor can detect scarred or fatty liver tissue
Diagnosing liver damage earlier could help to prevent liver failure in many patients.
Imaging method reveals a “symphony of cellular activities”
Fluorescent imaging technique simultaneously captures different signal types from multiple locations in a live cell.
A hunger for social contact
Neuroscientists find that isolation provokes brain activity similar to that seen during hunger cravings.