Biology

Researchers have developed a new way of imaging the middle ear using infrared light, which they say could provide much more accurate diagnosis of ear infections.

A new eye on the middle ear

Shortwave infrared instrument from MIT could see deeper, help improve diagnosis of ear infections.

August 22, 2016

“This place is remarkable,” Alfredo Alexander-Katz, the Walter Henry Gale Associate Professor of Materials Science and Engineering, says of MIT. “You can throw any crazy idea out there” and then pursue it.

Seeing nature through a molecular engineer’s eye

Alfredo Alexander-Katz probes systems in action, from clotting blood to walking molecules.

August 22, 2016

Researchers at MIT have for the first time identified the structure of class I fumarate hydratase enzyme, which could be a target for drugs combatting diseases prevalent in the developing world.

Targeting neglected diseases

New enzyme-mapping advance could help drug development.

August 15, 2016

Membrane structures in plant xylem from different species are being investigated for use in water filtration.

J-WAFS Solutions program awards $750,000 in commercialization grants

Four new projects and one renewal receive $150,000 in funding for 2016-2017.

August 12, 2016

Clockwise from top left: Cathy Drennan, professor of chemistry and biology at MIT; Squire Booker, a professor of chemistry and of biochemistry and molecular biology at Penn State; Martin McLaughlin ’15; and an image of LipA.

Research by MIT undergrad helps crack chemical mystery

Study finds enzyme “cannibalizes” itself to perform an essential reaction.

August 8, 2016

A new microfluidic device that replicates the neuromuscular junction — the vital connection where nerve meets muscle — contains a small cluster of neurons (green) and a single muscle fiber (red). A fluorescence image, bottom, shows the motor neurons sending out axons toward a muscle strip over a distance of about 1 millimeter.

Replicating the connection between muscles and nerves

New chip could help test drugs for ALS, other neuromuscular disorders.

August 3, 2016

“I love to work on new ideas and develop new kinds of tools to tackle basic questions,” says PhD student Tim Wang.

Targeting genes by the thousands

PhD student Tim Wang uses CRISPR to take a big-picture approach to cancer research.

August 2, 2016

A new, portable production system is designed to manufacture a range of biopharmaceuticals on demand. The principal component of the microbioreactor is a plastic chip with microfluidic circuits (green), optical sensors (red and blue circles) for monitoring oxygen and acidity, and a filter to retain the cells while the therapeutic protein is extracted (white circle).

Portable device produces biopharmaceuticals on demand

System would use microbes for manufacturing small amounts of vaccines and other therapies.

July 29, 2016

In humans and most other organisms, a circadian clock governed by light regulates the timing of key aspects of human physiology, by controlling cellular activities such as metabolism and division.

Why working the night shift can pose a cancer risk

New study reveals a link between circadian clock disruption and tumor growth.

July 28, 2016

MIT and Broad Institute postdoc Ilana Brito sampled not only the human microbiome in the remote villages in Fiji she studied, but also the reservoirs of microbes in the community.

Microbiome genes on the move

Largest metagenomic view of the developing world uncovers “mobile genes” that reveal how culture shapes the human microbiome.

July 14, 2016

“It’s intuitive that if a bunch of people are randomly walking around an area, the number of times they bump into each other will be a surrogate of the population density,” says Cameron Musco, an MIT graduate student in electrical engineering and computer science. “What we’re doing is giving a rigorous analysis behind that intuition, and also saying that the estimate is a very good estim...

Exploring networks efficiently

Analysis of ant colony behavior could yield better algorithms for network communication.

July 13, 2016

“How lithium acts on the brain has been this great mystery of psychopharmacology,” says Joshua Meisel, an MIT postdoc and lead author of a new study. “There are hypotheses, but nothing’s been proven.”

New clue to how lithium works in the brain

Biologists find a possible explanation for why the drug helps bipolar patients.

July 7, 2016

Mapping molecular neighborhoods

Associate Professor Ernest Fraenkel uses biological network modeling to identify new targets for disease.

July 5, 2016

A photo of three microfluidic devices filled with food color dyes. The device, about the size of a credit card, is designed to help scientists narrow in on safe ranges of electric fields that might be used to noninvasively treat breast, lung, and other forms of cancer.

New microfluidic device offers means for studying electric field cancer therapy

Low-intensity fields keep malignant cells from spreading, while preserving healthy cells.

July 5, 2016

“This nanoformulation approach allows us to make vaccines against new diseases in only seven days, allowing the potential to deal with sudden outbreaks or make rapid modifications and improvements,” says Daniel Anderson, an associate professor in MIT’s Department of Chemical Engineering and a member of MIT’s Koch Institute for Integrative Cancer Research and Institute for Medical Engineeri...

Engineers design programmable RNA vaccines

Tests in mice show the vaccines work against Ebola, influenza, and a common parasite.

July 4, 2016

MIT News | Massachusetts Institute of Technology

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