Engineers create an inhalable form of messenger RNA
Patients with lung disease could find relief by breathing in messenger RNA molecules.
Tracking the footprints of protein synthesis
Researchers refine a method to quantify protein production, show that the precision with which bacteria and eukaryotes tune their gene expression is remarkably similar.
Measuring cancer cell “fitness” reveals drug susceptibility
Together, cell growth rate and gene expression shed light on why some tumor cells survive treatment.
New CRISPR tool opens up more of the genome for editing
Enzyme can target almost half of the genome’s “ZIP codes” and could enable editing of many more disease-specific mutations.
This RNA-based technique could make gene therapy more effective
Biological engineers design RNA circuits that enable precise control over the dose of therapeutic protein a patient receives.
Ankur Jain joins Whitehead Institute and the Department of Biology
Biophysicist will investigate the biology of RNA aggregation.
Decoding RNA-protein interactions
Scientists leverage one step, unbiased method to characterize the binding preferences of more than 70 human RNA-binding proteins.
Network of diverse noncoding RNAs acts in the brain
Scientists identify the first known network consisting of three types of regulatory RNAs.
Scientists find different cell types contain the same enzyme ratios
New discovery suggests that all life may share a common design principle.
Researchers advance CRISPR-based tool for diagnosing disease
With SHERLOCK, a strip of paper can now indicate presence of pathogens, tumor DNA, or any genetic signature of interest.
Researchers engineer CRISPR to edit single RNA letters in human cells
“REPAIR” system edits RNA, rather than DNA; has potential to treat diseases without permanently affecting the genome.
New technique scours the genome for genes that combat disease
Biological engineers identify genes that protect against protein linked to Parkinson’s disease.
JoAnne Stubbe wins Pearl Meister Greengard Prize
Awarded annually by The Rockefeller University, the award recognizes accomplishments of outstanding women in science.
Scientists unveil CRISPR-based diagnostic platform
New system adapts tool known for gene editing; to be used in rapid, inexpensive disease diagnosis.
Progress toward a Zika vaccine
Researchers program RNA nanoparticles that could protect against the virus.