HIV genome bends over backwards to help virus take over cells
Differently shaped RNA molecules allow HIV to express different genes from the same RNA sequence.
3 Questions: Hadley Sikes on searching for a Covid-19 protein test
Chemical engineer aims to create a test that can work in 10 minutes and doesn’t require specialized instruments or laboratory infrastructure.
Technique identifies T cells primed for certain allergies or infections
Researchers develop a method to isolate and sequence the RNA of T cells that react to a specific target.
Ankur Jain awarded Packard Foundation Fellowship
Whitehead Institute member and assistant professor of biology receives one of the most prestigious non-governmental awards for early-career scientists.
Delivery system can make RNA vaccines more powerful
Vaccines packaged in novel nanoparticles could offer a new way to fight cancer and infectious diseases.
An emerging view of RNA transcription and splicing
Whitehead Institute scientists find chemical modification contributes to trafficking between non-membrane-bound compartments that control gene expression.
New CRISPR platform expands RNA editing capabilities
The new system, dubbed RESCUE, allows RNA edits to be made that were not previously possible.
A chemical approach to imaging cells from the inside
Researchers develop a new microscopy system for creating maps of cells, using chemical reactions to encode spatial information.
New gene-editing system precisely inserts large DNA sequences into cellular DNA
Researchers identify and develop new CRISPR-associated transposase system for targeted integration of DNA, adding key capabilities to gene-editing technology.
A “biomultimeter” lets scientists measure RNA and protein production in real-time
Fluorescent tagging system can expedite the process of designing genes and personalizing medicine.
Earliest life may have arisen in ponds, not oceans
Study finds shallow bodies of water were probably more suitable for Earth’s first life forms.
The evolving definition of a gene
Professor Gerald Fink, a pioneer in the field of genetics, delivers the annual Killian Lecture.
Academic institutions grant commercial license for CRISPR-based SHERLOCK diagnostic technology in developed world
Rights are protected for broad use in developing world and for public health needs.
Tissue model reveals how RNA will act on the liver
Studies could speed the development of new treatments for liver disease.
Scientists engineer new CRISPR platform for DNA targeting
CRISPR team harnesses new Cas12b enzyme for use in eukaryotic cells, adding to the CRISPR toolbox.