National Institutes of Health (NIH)

“Even though there has been a lot of high-resolution, atomic level structural work on amyloids by solid-state NMR, people have really not studied the metal-binding aspects,” says professor Mei Hong.

Chemists reveal amyloid structure

Discovery of how amyloids bind metal ions sheds light on protein function.

May 29, 2017

Researchers produced colored images on culture plates by using red, green, and blue lights to control the pigment produced by bacteria with “multicolor vision.” The image has been color-corrected in Photoshop to improve contrast.

Bacteria with multicolor vision

Red, green, and blue light can be used to control gene expression in engineered E. coli.

May 26, 2017

MIT students and postdocs with the Science Policy Initiative participated in Congressional Visits Day for the 11th consecutive year.

MIT students and postdocs advocate for science and engineering funding on Capitol Hill

Members of MIT's Science Policy Initiative meet with members of Congress on Science-Engineering-Technology Congressional Visits Day.

May 11, 2017

MIT researchers created this colon tumor by delivering RNA encapsulated in lipid nanoparticles to the colon. The RNA can activate or delete specific genes, leading to tumor growth.

New model could speed up colon cancer research

Introducing genetic mutations with CRISPR offers a fast and accurate way to simulate the disease.

May 1, 2017

Wireless power could enable ingestible electronics

Small sensors or drug delivery devices could reside in the GI tract indefinitely.

April 27, 2017

Center for Environmental Health Sciences announces 2017 call for pilot project proposals

Proposals are invited for basic and translational environmental health sciences research.

April 18, 2017

MIT Professor Tyler Jacks, director of the Koch Institute for Integrative Cancer Research, recently testified before a U.S. House Committee on Oversight and Government Reform hearing titled, “Federally Funded Cancer Research: Coordination and Innovation.” He is seen here presenting recommendations from the Cancer Moonshot Blue Ribbon Panel report to the National Cancer Advisory Board in Septem...

Tyler Jacks: NIH budget cuts would have “devastating” effects on progress against cancer

Koch Institute director advocates support for biomedical research in testimony before the House Committee on Oversight and Government Reform.

April 10, 2017

Researchers have found a way to make tiny particles that can be injected into the body, where they emit short-wave infrared light. The advance may open up a new way of making detailed images of internal body structures such as fine networks of blood vessels.

Nanoparticles open new window for biological imaging

“Quantum dots” that emit infrared light enable highly detailed images of internal body structures.

April 10, 2017

In a study of 365,000 NIH grants — nearly every NIH grant awarded for 27 years — researchers found that 31 percent produce articles that are later cited by patents in the biomedical sector.

Study: NIH funding generates large numbers of private-sector patents

New research shows large spillover from the lab to commercial activity.

March 30, 2017

Scientists identify brain circuit that drives pleasure-inducing behavior

Surprisingly, the neurons are located in a brain region thought to be linked with fear.

March 22, 2017

The immune system often builds up a wall of dense scar tissue around implanted medical devices, a process known as fibrosis. The cell shown in blue represents a macrophage that has been blocked from initiating fibrosis.

Study points a way to better implants

Selectively blocking immune cells can prevent formation of scar tissue around medical devices.

March 20, 2017

A new MIT transmitter that measures dopamine overcomes limitations of earlier transmitters, providing accurate readings for longer periods of time and covering more of the brain.

Precise technique tracks dopamine in the brain

New sensor could reveal the neurotransmitter’s role in learning and habit formation.

March 3, 2017

A team of MIT biological engineers has developed a method to measure levels of the iron-containing protein heme inside the malaria parasite. “One of our long-term goals is ultimately being able to tie insights from these studies back to thinking about drug discovery and targeting pathways that regulate heme,” says Jacquin Niles, an MIT associate professor of biological engineering.

Taking aim at a key malaria molecule

Measuring the parasite’s heme levels could help scientists develop better antimalarial drugs.

February 27, 2017

Obstructive sleep apnea is caused by a narrowing of the airway that cuts off breathing, and people who are obese are at higher risk for the disorder. MIT researchers have discovered that a dietary supplement called yohimbine reverses the root cause of obstructive sleep apnea in an animal model.

A possible new approach to stopping obstructive sleep apnea

Dietary supplement derived from tree bark shows promise for treating the disorder.

February 23, 2017

This image shows large clonal colonies of cochlear progenitor cells formed from single cells and converted into high-purity colonies of hair cells (cyan) with intricate hair bundles (red).

Drug treatment could combat hearing loss

Researchers discover a drug combination that can regenerate hair cells in the inner ear.

February 21, 2017

MIT News | Massachusetts Institute of Technology

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