Technique recovers lost single-cell RNA-sequencing information
Boosting the efficiency of single-cell RNA-sequencing helps reveal subtle differences between healthy and dysfunctional cells.
Koch Institute
Three from MIT receive National Health Institute Awards
Michael Birnbaum, Anders Hansen, and Tami Lieberman receive NIH Director’s New Innovator Awards from the NIH Common Fund’s High-Risk, High-Reward Research program.
Nanoparticles can turn off genes in bone marrow cells
Using these new particles, researchers could develop treatments for heart disease and other conditions.
Cancer researchers collaborate, target DNA damage repair pathways for cancer therapy
MIT researchers find blocking the expression of the genes XPA and MK2 enhances the tumor-shrinking effects of platinum-based chemotherapies in p53-mutated cancers.
Regina Barzilay wins $1M Association for the Advancement of Artificial Intelligence Squirrel AI award
MIT professor announced as award’s first recipient for work in cancer diagnosis and drug synthesis.
Synthetic coating for the GI tract could deliver drugs or aid in digestion
MIT engineers devise a temporary film that may help treat diabetes, infections, and other conditions.
Rapid antibody development yields possible treatment for yellow fever
The experimental drug has shown promise in early-stage clinical trials conducted in Singapore.
Gene-controlling mechanisms play key role in cancer progression
Study finds “epigenomic” alterations evolve as lung tumors become more aggressive and metastasize.
Exhaled biomarkers can reveal lung disease
Specialized nanoparticles create a “breath signal” that could be used to diagnose pneumonia and other infectious or genetic diseases.
COMMANDing drug delivery
A new computational method fine-tunes delivery of therapeutics to specific brain regions.
Engineers design a reusable, silicone rubber face mask
The prototype mask, which includes an N95 filter, can be easily sterilized and worn many times.
Helping drug-delivering particles squeeze through a syringe
MIT engineers are using computing modeling to prevent microparticles from clogging during injections.
Engineers use “DNA origami” to identify vaccine design rules
In lab tests, virus-like DNA structures coated with viral proteins provoke a strong immune response in human B cells.
How cancer drugs find their targets
Certain cancer therapeutics concentrate within cells — a finding that could change the way scientists think about drug design.
A focused approach to imaging neural activity in the brain
New molecule for imaging calcium in neurons reduces crosstalk from neighboring neurons.