Extra chromosome alters chromosomal conformation and DNA accessibility in neural progenitor cells; study establishes senescence as a potentially targetable mechanism for future treatment.
Unbiased, high-throughput analysis pipeline improves utility of “minibrains” for understanding development and diseases such as Zika infection.
MIT researchers pinpoint mechanism and demonstrate that drugs could help.
Molecules called ketone bodies may improve stem cells’ ability to regenerate new intestinal tissue.
Method boosts differentiation of stem cells into mature blood cell types, may help leukemia and lymphoma patients.
Researchers generate an intestinal cell mimic that can be harnessed in studies of diseases such as inflammatory bowel disease.
Blocking the transition to a more aggressive state could offer a new treatment strategy.