A high-fat diet sets off metabolic dysfunction in cells, leading to weight gain
Researchers also found these effects can be reversed by treatment with an antioxidant.
Scientists discover potential new targets for Alzheimer’s drugs
Pathways involved in DNA repair and other cellular functions could contribute to the development of Alzheimer’s.
With AI, researchers predict the location of virtually any protein within a human cell
Trained with a joint understanding of protein and cell behavior, the model could help with diagnosing disease and developing new drugs.
Particles carrying multiple vaccine doses could reduce the need for follow-up shots
MIT engineers designed polymer microparticles that can deliver vaccines at predetermined times after injection.
Biologists identify targets for new pancreatic cancer treatments
Their study yielded hundreds of “cryptic” peptides that are found only on pancreatic tumor cells and could be targeted by vaccines or engineered T cells.
New molecular label could lead to simpler, faster tuberculosis tests
MIT chemists found a way to identify a complex sugar molecule in the cell walls of Mycobacterium tuberculosis, the world’s deadliest pathogen.
The age-old problem of long-term care
Informal help is a huge share of elder care in the U.S., a burden that is only set to expand. A new book explores different countries’ solutions.
Study of facial bacteria could lead to probiotics that promote healthy skin
During the early teen years, many new strains of C. acnes colonize the skin on our faces. This could be an optimal time for probiotic treatment.
Gene circuits enable more precise control of gene therapy
The circuits could help researchers develop new treatments for fragile X syndrome and other diseases caused by mutations of a single gene.
New study reveals how cleft lip and cleft palate can arise
MIT biologists have found that defects in some transfer RNA molecules can lead to the formation of these common conditions.
Molecules that fight infection also act on the brain, inducing anxiety or sociability
New research on a cytokine called IL-17 adds to growing evidence that immune molecules can influence behavior during illness.
Taking the “training wheels” off clean energy
At the 2025 MIT Energy Conference, energy leaders from around the world discussed how to make green technologies competitive with fossil fuels.
To the brain, Esperanto and Klingon appear the same as English or Mandarin
A new study finds natural and invented languages elicit similar responses in the brain’s language-processing network.
MIT engineers turn skin cells directly into neurons for cell therapy
A new, highly efficient process for performing this conversion could make it easier to develop therapies for spinal cord injuries or diseases like ALS.
Study: Tuberculosis relies on protective genes during airborne transmission
The findings provide new drug targets for stopping the infection’s spread.