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Findings from the Whitehead Institute at MIT not only help illuminate the biology of a well-known cancer chemotherapy, but also suggest a simple dietary supplement that could help broaden its therapeutic window and reduce its toxicity.

Scientists sharpen the edges of cancer chemotherapy

Whitehead team deploys CRISPR tools to better understand and uncover ways of improving methotrexate, a popular chemotherapy drug.

July 12, 2018

Fraternal twins Miles (left) and Malik (right) George will matriculate at MIT this fall.

Dynamic duo

Incoming first-year students Malik and Miles George double down on their dream of attending MIT.

July 3, 2018

Left to right: Laurie Boyer, Matt Shoulders, and Feng Zhang.

Advancing knowledge in medical and genetic sciences

Three MIT faculty members selected for funding from the G. Harold and Leila Y. Mathers Foundation.

June 26, 2018

Alejandra Falla PhD '18 holds her newborn, Clara, during the 2018 Commencement exercises.

Scene at MIT: PhD baby and her amazing mama

A new daughter helped Alejandra Falla PhD ’18 gain perspective on life — and her tiny MIT regalia stole the show at Commencement.

June 12, 2018

MIT neuroscientists have performed a comprehensive study of the APOE4 gene, which increases risk for Alzheimer’s disease, and the more common form of the gene, APOE3.

Neuroscientists discover roles of gene linked to Alzheimer’s

Study reveals why people with the APOE4 gene have higher risk of the disease.

May 31, 2018

Ed Boyden (left) and Feng Zhang have been named HHMI investigators.

Ed Boyden and Feng Zhang named Howard Hughes Medical Institute Investigators

MIT faculty members are among 19 top scientists selected from across the nation.

May 23, 2018

MIT’s four new NAS members are (from left): Feng Zhang, Mehran Kardar, Amy Finkelstein, and Xiao-Gang Wen.

National Academy of Sciences elects four MIT professors for 2018

Finkelstein, Kardar, Wen, and Zhang honored for research achievements.

May 1, 2018

A collection of SHERLOCK paper test strips. (Left) Unused paper strips, (middle) paper tests displaying a negative SHERLOCK readout, and (right) paper tests displaying a positive SHERLOCK readout.

Researchers advance CRISPR-based tool for diagnosing disease

With SHERLOCK, a strip of paper can now indicate presence of pathogens, tumor DNA, or any genetic signature of interest.

February 15, 2018

New Whitehead Institute research may prove to be a useful paradigm for targeting diseases caused by abnormal methylation.

Study: Fragile X syndrome neurons can be restored

Whitehead Institute researchers are using a modified CRISPR/Cas9-guided activation strategy to investigate the most frequent cause of intellectual disability in males.

February 15, 2018

From left to right: Polina Anikeeva, the Class of 1942 Associate Professor in the Department of Materials Science and Engineering and associate director of the Research Laboratory of Electronics, and Feng Zhang, the James and Patricia Poitras ’63 Professor in Neuroscience at the McGovern Institute, a core member of the Broad Institute, and an associate professor in the departments of Brain and C...

Polina Anikeeva and Feng Zhang awarded 2018 Vilcek Prize

Prize recognizes contributions to biomedical research made by immigrant scientists.

February 1, 2018

George Church gave the first lecture in the Department of Biology’s four-part IAP seminar series, Biology at Transformative Frontiers.

Reading and writing DNA

Department of Biology kicks off IAP seminar series with a lecture by synthetic-biology visionary George Church.

January 31, 2018

In a new study, MIT researchers have developed nanoparticles that can deliver the CRISPR genome-editing system and specifically modify genes, eliminating the need to use viruses for delivery.

CRISPR-carrying nanoparticles edit the genome

New delivery system developed by MIT team deletes disease-causing genes and reduces cholesterol.

November 13, 2017

A new “REPAIR” system edits RNA, rather than DNA.

Researchers engineer CRISPR to edit single RNA letters in human cells

“REPAIR” system edits RNA, rather than DNA; has potential to treat diseases without permanently affecting the genome.

October 25, 2017

MIT researchers have adapted the CRISPR genome-editing system to identify genes that protect cells from a protein associated with Parkinson’s disease.

New technique scours the genome for genes that combat disease

Biological engineers identify genes that protect against protein linked to Parkinson’s disease.

October 12, 2017

Ten from MIT and the Broad Institute recently received NIH Director's Awards. Top row (l-r): Feng Zhang, Kay Tye, Kevin Esvelt, Fei Chen; Bottom row (l-r): Gabriela Schlau-Cohen, Ahmed Badran, Hilary Finucane, Ed Boyden. Not pictured: Paul Blainey and Evan Macosko.

Ten researchers from MIT and Broad receive NIH Director’s Awards

Awards support high-risk, high-impact biomedical research.

October 5, 2017

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