Helping the immune system attack tumors
Stefani Spranger is working to discover why some cancers don’t respond to immunotherapy, in hopes of making them more vulnerable to it.
Department
Biology
Five from MIT named 2025 Gates Cambridge Scholars
Markey Freudenburg-Puricelli; Christina Kim ’24; Abigail Schipper ’24; Sera Tolgay MCP ’18, SM ’18; and Rachel Zhang ’21 will pursue graduate studies at Cambridge University in the U.K.
AI system predicts protein fragments that can bind to or inhibit a target
FragFold, developed by MIT Biology researchers, is a computational method with potential for impact on biological research and therapeutic applications.
Professor Anthony Sinskey, biologist, inventor, entrepreneur, and Center for Biomedical Innovation co-founder, dies at 84
Colleagues remember the longtime MIT professor as a supportive, energetic collaborator who seemed to know everyone at the Institute.
MIT biologists discover a new type of control over RNA splicing
They identified proteins that influence splicing of about half of all human introns, allowing for more complex types of gene regulation.
AI model deciphers the code in proteins that tells them where to go
Whitehead Institute and CSAIL researchers created a machine-learning model to predict and generate protein localization, with implications for understanding and remedying disease.
From bench to bedside, and beyond
In the United States and abroad, Matthew Dolan ’81 has served as a leader in immunology and virology.
Kingdoms collide as bacteria and cells form captivating connections
Studying the pathogen R. parkeri, researchers discovered the first evidence of extensive and stable interkingdom contacts between a pathogen and a eukaryotic organelle.
New autism research projects represent a broad range of approaches to achieving a shared goal
At a symposium of the Simons Center for the Social Brain, six speakers described a diversity of recently launched studies aimed at improving understanding of the autistic brain.
Artifacts from a half-century of cancer research
Ten objects on display in the Koch Institute Public Galleries offer uncommon insights into the people and progress of MIT's cancer research community.
Photos: 2024 Nobel winners with MIT ties honored in Stockholm
Laureates participated in various Nobel Week events, including lectures, a concert, a banquet, and the Nobel ceremony on Dec. 10.
Cellular traffic congestion in chronic diseases suggests new therapeutic targets
Chronic diseases like diabetes are prevalent, costly, and challenging to treat. A common denominator driving them may be a promising new therapeutic target.
A blueprint for better cancer immunotherapies
By examining antigen architectures, MIT researchers built a therapeutic cancer vaccine that may improve tumor response to immune checkpoint blockade treatments.
When a cell protector collaborates with a killer
New research reveals what it takes for a protein that is best known for protecting cells against death to take on the opposite role.
Killing the messenger
A newly characterized anti-viral defense system in bacteria aborts infection through a novel mechanism by chemically altering mRNA.