Biological Engineering

Feng Zhang of MIT and the Broad Institute was named a runner-up for TIME's 2016 Person of the Year for his work on CRISPR gene editing. Zhang shared the honor with Emmanuelle Charpentier at the Max Planck Institute in Berlin; Jennifer Doudna at the University of California at Berkeley; Carl June at the University of Pennsylvania; and Kathy Niakan at the Francis Crick Institute in London.

Feng Zhang named a runner-up for TIME’s 2016 Person of the Year

MIT and Broad Institute scientist shares recognition with four other scientists for developing CRISPR gene-editing systems.

December 7, 2016

“…[I]f humans behave similarly to mice in response to this treatment, I would say the potential is just enormous, because it’s so noninvasive, and it’s so accessible,” says Li-Huei Tsai, the Picower Professor of Neuroscience, when describing a new treatment for Alzheimer’s disease.

Unique visual stimulation may be new treatment for Alzheimer’s

Noninvasive technique reduces beta amyloid plaques in mouse models of Alzheimer’s disease.

December 7, 2016

MIT researchers have designed protein-based sensors that can dilate blood vessels in the brain. This dilation can be imaged with magnetic resonance imaging (MRI), as seen on the left side of this scan.

A radiation-free approach to imaging molecules in the brain

New probe induces blood flow changes that can be seen by MRI.

December 2, 2016

MIT researchers have developed a way to isolate genetic circuits within individual synthetic “cells,” preventing the circuits from disrupting each other.

Researchers create synthetic cells to isolate genetic circuits

Encapsulating molecular components in artificial membranes offers more flexibility in designing circuits.

November 14, 2016

Four nucleotides, abbreviated A, C, G, and T, spell out DNA sequences that code for all of the proteins cells need. MIT researchers have now discovered another layer of control, mediated by transfer RNA, that helps cells to rapidly divert resources in emergency situations.

Cracking the code for dormant bacteria

Newly discovered genetic code controls bacterial survival during infections.

November 11, 2016

A team of researchers at MIT, the University of Brasilia, and the University of British Columbia has now engineered an antimicrobial peptide that can destroy many types of bacteria, including some that are resistant to most antibiotics.

Engineers design a new weapon against bacteria

Antimicrobial peptides can kill strains resistant to existing antibiotics.

November 2, 2016

When cells suffer DNA damage, there are several different pathways that can kick in to help repair it, depending on the type of damage. Cells from different people and different tumors vary greatly in their ability to repair DNA damage, and scientists have been pursuing measurements of this ability as a way to predict how patients will respond to DNA-damaging chemotherapy.

Predicting cancer cells’ response to chemotherapy

Measuring DNA repair capability can reveal tumors’ sensitivity to drugs.

November 2, 2016

David H. Koch Institute Professor Robert Langer speaks with MIT students as part of the "Failures in Graduate School" seminar series.

Robert Langer reflects on failure, resilience, and making an impact

Institute Professor and world-renowned engineer shares his experiences as an MIT grad student as part of the “Failures in Graduate School” series.

October 31, 2016

T cells — immune cells that are targeted to find and destroy a particular antigen — are key to the adaptive immune response. In this image, the top row shows few T cells in untreated mice, while the bottom rows show many T cells produced after immunotherapy treatment.

Fighting cancer with the power of immunity

New treatment elicits two-pronged immune response that destroys tumors in mice.

October 24, 2016

Molecular fMRI data showing signal changes from serotonin sensors in the absence (left) and presence (right) of the antidepressant Prozac, with each square denoting an individual brain voxel. Red squares indicate the signal has increased, as more serotonin is absorbed into neurons; blue squares indicate the signal has decreased, as less serotonin is absorbed into neurons. Dotted and solid lines gr...

Mapping serotonin dynamics in the living brain

Imaging technique that creates 3-D video of serotonin transport could aid antidepressant development.

October 20, 2016

Margaret Guo '16, a decorated MIT swimmer, was named the 2016 NCAA Woman of the Year.

Margaret Guo '16 named NCAA Woman of the Year

A decorated swimmer and engineer, Guo is the first MIT student-athlete and just the fourth Division III student-athlete to ever receive the honor.

October 19, 2016

Researchers have developed a novel way to test tumors for drug susceptibility. They successfully tested this approach with a very aggressive type of brain cancer called glioblastoma multiforme and a type of blood cancer, pictured here in dark purple, known as acute lymphoblastic leukemia.

A new strategy for choosing cancer drugs

Device can predict tumor responses by measuring cell growth after drug exposure.

October 10, 2016

U.S. Secretary of Commerce Penny Pritzker and MIT President L. Rafael Reif discuss innovation and entrepreneurship at an event hosted by the MIT Innovation Initiative.

Advancing manufacturing innovation on campus and online

The White House highlights MIT’s latest efforts as part of National Manufacturing Day.

October 7, 2016

MIT Communication Lab Director Jaime Goldstein says a new online tool will help deadline-driven graduate students write at any hour of the day.

Engineer, explain thyself

A new online tool helps graduate students communicate — in their own languages.

September 27, 2016

Clockwise from top left: MIT professors Ed Boyden, Jacquin Niles, Feng Zhang, and Matthew Vander Heiden have been named HHMI Faculty Scholars.

Four MIT professors named inaugural Faculty Scholars

New program from the Howard Hughes Medical Institute, Simons Foundation, and Bill and Melinda Gates Foundation supports early-career scientists.

September 22, 2016

MIT News | Massachusetts Institute of Technology

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