Biologists build proteins that avoid crosstalk with existing molecules
Engineered signaling pathways could offer a new way to build synthetic biology circuits.
Drug combination reverses hypersensitivity to noise
Findings in mice suggest targeting certain brain circuits could offer new ways to treat some neurological disorders.
Whitehead Institute team resolves structure of master growth regulator
New research reveals how mTORC1 docks at lysosomal surface.
Study reveals how mucus tames microbes
Specialized sugar molecules called glycans can disarm opportunistic pathogens and prevent infection.
New method visualizes groups of neurons as they compute
Fluorescent probe could allow scientists to watch circuits within the brain and link their activity to specific behaviors.
New capsule can orally deliver drugs that usually have to be injected
Coated pill carries microneedles that deliver insulin and other drugs to the lining of the small intestine.
Engineered viruses could fight drug resistance
By tweaking bacteriophage genomes, MIT team creates a new weapon to combat infection.
Technique can image individual proteins within synapses
Rapid imaging method could help reveal how conditions such as autism affect brain cells.
Perception of musical pitch varies across cultures
How people interpret musical notes depends on the types of music they have listened to, researchers find.
Using machine learning to estimate risk of cardiovascular death
CSAIL system uses a patient's ECG signal to estimate potential for cardiovascular death.
A much less invasive way to monitor pressure in the brain
New technique could help doctors determine whether patients are at risk from elevated pressure.
Study links certain metabolites to stem cell function in the intestine
Molecules called ketone bodies may improve stem cells’ ability to regenerate new intestinal tissue.
High-precision technique stores cellular “memory” in DNA
Engineers program human and bacterial cells to keep a record of complex molecular events.
To divide or not to divide?
Whitehead Institute team reveals molecular program that controls cells’ capacity for division.
A new way to deliver drugs with pinpoint targeting
Magnetic particles allow drugs to be released at precise times and in specific areas.