Turning on an immune pathway in tumors could lead to their destruction
MIT researchers show they can use messenger RNA to activate the pathway and trigger the immune system to attack tumors.
Immune-informed brain aging research offers new treatment possibilities, speakers say
Speakers at MIT’s Aging Brain Initiative symposium described how immune system factors during aging contribute to Alzheimer’s, Parkinson’s and other conditions. The field is leveraging that knowledge to develop new therapies.
MIT launches a “moonshot for menstruation science”
The Fairbairn Menstruation Science Fund will allow researchers to accelerate the understanding and treatment of often-neglected diseases that tend to be more common in women.
New AI system uncovers hidden cell subtypes, boosts precision medicine
CellLENS reveals hidden patterns in cell behavior within tissues, offering deeper insights into cell heterogeneity — vital for advancing cancer immunotherapy.
First-of-its-kind device profiles newborns’ immune function
The BiophysicaL Immune Profiling for Infants (BLIPI) profiles an infant’s immune system in under 15 minutes, using just a single drop of blood.
Technique rapidly measures cells’ density, reflecting health and developmental state
The method could help predict whether immunotherapies will work in a patient or how a tumor will respond to drug treatment.
Molecules that fight infection also act on the brain, inducing anxiety or sociability
New research on a cytokine called IL-17 adds to growing evidence that immune molecules can influence behavior during illness.
Helping the immune system attack tumors
Stefani Spranger is working to discover why some cancers don’t respond to immunotherapy, in hopes of making them more vulnerable to it.
From bench to bedside, and beyond
In the United States and abroad, Matthew Dolan ’81 has served as a leader in immunology and virology.
Is this the new playbook for curing rare childhood diseases?
When his son received a devastating diagnosis, Fernando Goldsztein MBA ’03 founded an initiative to help him and others.
A new vaccine approach could help combat future coronavirus pandemics
The nanoparticle-based vaccine shows promise against many variants of SARS-CoV-2, as well as related sarbecoviruses that could jump to humans.
A blueprint for better cancer immunotherapies
By examining antigen architectures, MIT researchers built a therapeutic cancer vaccine that may improve tumor response to immune checkpoint blockade treatments.
A two-dose schedule could make HIV vaccines more effective
MIT researchers find that the first dose primes the immune system, helping it to generate a strong response to the second dose, a week later.
A new way to reprogram immune cells and direct them toward anti-tumor immunity
MIT scientists’ discovery yields a potent immune response, could be used to develop a potential tumor vaccine.
A new way to miniaturize cell production for cancer treatment
A chip the size of a pack of cards uses fewer resources and a smaller footprint than existing automated manufacturing platforms and could lead to more affordable cell therapy manufacturing.