Immune action at a distance
MIT and MGH researchers design a local, gel-based drug-delivery platform that may provoke a system-wide immune response to metastatic tumors.
Molecule reduces inflammation in Alzheimer’s models
A potential new Alzheimer’s drug represses the harmful inflammatory response of the brain’s immune cells, reducing disease pathology, preserving neurons, and improving cognition in preclinical tests.
A snapshot of cancer vaccine development
The Koch Institute’s Annual Symposium highlights emerging successes and challenges in the advancement of vaccines to prevent and treat cancer.
Study finds a surprising new role for a major immune regulator
In addition to turning on genes involved in cell defense, the STING protein also acts as an ion channel, allowing it to control a wide variety of immune responses.
Newly discovered bacterial communication system aids antimicrobial resistance
SMART researchers find the enzyme RlmN, which directly senses chemical and environmental stresses, can be targeted in drug development.
Atlas of human brain blood vessels highlights changes in Alzheimer’s disease
MIT researchers characterize gene expression patterns for 22,500 brain vascular cells across 428 donors, revealing insights for Alzheimer’s onset and potential treatments.
Putting the STING into cancer immunotherapy
A cancer vaccine combining checkpoint blockade therapy and a STING-activating drug eliminates tumors and prevents recurrence in mice.
A shot in the arm
Researchers develop new, patient-friendly hydrogel platform for administering lifesaving biologics.
Creating a versatile vaccine to take on Covid-19 in its many guises
Aided by machine learning, scientists are working to develop a vaccine that would be effective against all SARS-CoV-2 strains.
3 Questions: Cullen Buie on a new era for cell therapies
The associate professor of MechE reflects on how his company, Kytopen, has grown and shifted focus in developing safer immunotherapies.
Why lung cancer doesn’t respond well to immunotherapy
A new study reveals that lymph nodes near the lungs create an environment that weakens T-cell responses to tumors.
2022-23 Takeda Fellows: Leveraging AI to positively impact human health
New fellows are working on health records, robot control, pandemic preparedness, brain injuries, and more.
Seven with MIT ties receive awards from the American Physical Society
Professors Arup Chakraborty, Lina Necib, and Ronald Fernando Garcia Ruiz as well as Yuan Cao SM ’16, PhD ’20; Alina Kononov ’14; Elliott H. Lieb ’53; Haocun Yu PhD ’20; and others honored for contributions to physics.
Building a bridge between neuroscience and immunology
Gloria Choi’s studies of how the immune system and nervous system influence each other could yield new approaches to treating neurological disorders.
With fractured genomes, Alzheimer’s neurons call for help
Study indicates ailing neurons may instigate an inflammatory response from the brain’s microglia immune cells.