MIT scientists discover new antiviral defense system in bacteria
Prokaryotes can detect hallmark viral proteins and trigger cell death through a process seen across all domains of life.
Prokaryotes can detect hallmark viral proteins and trigger cell death through a process seen across all domains of life.
Jonathan Weissman and collaborators used their single-cell sequencing tool Perturb-seq on every expressed gene in the human genome, linking each to its job in the cell.
MIT neuroscientists expand CRISPR toolkit with new, compact Cas7-11 enzyme.
A Climate Grand Challenges flagship project aims to reduce agriculture-driven emissions while making food crop plants heartier and more nutritious.
Udayan Umapathi SM ’17 and Will Langford SM ’14, PhD ’19 are co-founders of a Media Lab spinoff building a full-stack platform to enable automation for genomics and genetic engineering.
Exploring diversity among bacterial immune systems, McGovern Institute scientists uncovere a programmable system for precisely targeting and modifying RNA.
Researchers find RNA-guided enzymes are more diverse and widespread than previously believed.
Made of components found in the human body, the programmable system is a step toward safer, targeted delivery of gene editing and other molecular therapeutics.
Novel method, developed by McGovern Institute researchers, may lead to safer, more efficient gene therapies.
Applied computational biology discoveries vastly expand the range of CRISPR’s access to DNA sequences.
By introducing a gene variant associated with autism into monkeys, researchers hope to study treatment options for severe neurodevelopmental disorders.
Researchers identify and develop new CRISPR-associated transposase system for targeted integration of DNA, adding key capabilities to gene-editing technology.
CRISPR team harnesses new Cas12b enzyme for use in eukaryotic cells, adding to the CRISPR toolbox.
Enzyme can target almost half of the genome’s “ZIP codes” and could enable editing of many more disease-specific mutations.
With SHERLOCK, a strip of paper can now indicate presence of pathogens, tumor DNA, or any genetic signature of interest.