A new system can dial expression of synthetic genes up or down
The promoter editing system could be used to fine-tune gene therapy or to more efficiently reprogram cells for therapeutic use.
A more precise way to edit the genome
MIT researchers have dramatically lowered the error rate of prime editing, a technique that holds potential for treating many genetic disorders.
This MIT spinout is taking biomolecule storage out of the freezer
Cache DNA has developed technologies that can preserve biomolecules at room temperature to make storing and transporting samples less expensive and more reliable.
Study explains how a rare gene variant contributes to Alzheimer’s disease
Lipid metabolism and cell membrane function can be disrupted in the neurons of people who carry rare variants of ABCA7.
Study finds cell memory can be more like a dimmer dial than an on/off switch
The findings may redefine how cell identity is established and enable the creation of more sophisticated engineered tissues.
Remembering David Baltimore, influential biologist and founding director of the Whitehead Institute
The longtime MIT professor and Nobel laureate was a globally respected researcher, academic leader, and science policy visionary who guided the careers of generations of scientists.
Mapping cells in time and space: New tool reveals a detailed history of tumor growth
Researchers developed a tool to recreate cells’ family trees. Comparing cells’ lineages and locations within a tumor provided insights into factors shaping tumor growth.
Scientists apply optical pooled CRISPR screening to identify potential new Ebola drug targets
Combining powerful imaging, perturbational screening, and machine learning, researchers uncover new human host factors that alter Ebola’s ability to infect.
How to more efficiently study complex treatment interactions
A new approach for testing multiple treatment combinations at once could help scientists develop drugs for cancer or genetic disorders.
New method combines imaging and sequencing to study gene function in intact tissue
The approach collects multiple types of imaging and sequencing data from the same cells, leading to new insights into mouse liver biology.
In Down syndrome mice, 40Hz light and sound improve cognition, neurogenesis, connectivity
New evidence suggests sensory stimulation of gamma-frequency brain rhythm may promote broad-based restorative neurological health response.
Equipping living cells with logic gates to fight cancer
Founded by MIT researchers, Senti Bio is giving immune cells the ability to distinguish between healthy and cancerous cells.
New study reveals how cleft lip and cleft palate can arise
MIT biologists have found that defects in some transfer RNA molecules can lead to the formation of these common conditions.
Anders Sejr Hansen named Edgerton Award winner
MIT associate professor recognized for exceptional distinction in teaching, research, and service at MIT.
Restoring healthy gene expression with programmable therapeutics
CAMP4 Therapeutics is targeting regulatory RNA, whose role in gene expression was first described by co-founder and MIT Professor Richard Young.