Countering mitochondrial stress
Scientists discover a pathway that monitors a protein import into mitochondria and elicits a cellular response when the process goes awry.
Scientists find different cell types contain the same enzyme ratios
New discovery suggests that all life may share a common design principle.
Timothy Lu seeks to combat disease by reprogramming biological systems
Synthetic biologist hopes to develop treatments for cancer and other diseases.
Scientists deliver high-resolution glimpse of enzyme structure
New finding suggests differences in how humans and bacteria control production of DNA’s building blocks.
Researchers advance CRISPR-based tool for diagnosing disease
With SHERLOCK, a strip of paper can now indicate presence of pathogens, tumor DNA, or any genetic signature of interest.
Study: Fragile X syndrome neurons can be restored
Whitehead Institute researchers are using a modified CRISPR/Cas9-guided activation strategy to investigate the most frequent cause of intellectual disability in males.
Reading and writing DNA
Department of Biology kicks off IAP seminar series with a lecture by synthetic-biology visionary George Church.
How some facial malformations arise
Study explains why mutations that would seemingly affect all cells lead to face-specific birth defects.
New techniques give blood biopsies greater promise
Improved methods validate the use of blood samples for studying patients’ cancer genomes.
Researchers engineer CRISPR to edit single RNA letters in human cells
“REPAIR” system edits RNA, rather than DNA; has potential to treat diseases without permanently affecting the genome.
Gene circuit switches on inside cancer cells, triggers immune attack
Advance may open new pathways for cancer immunotherapy.
New technique scours the genome for genes that combat disease
Biological engineers identify genes that protect against protein linked to Parkinson’s disease.
JoAnne Stubbe wins Pearl Meister Greengard Prize
Awarded annually by The Rockefeller University, the award recognizes accomplishments of outstanding women in science.
Researchers identify molecular motor that transforms chromosomes
Experiments confirm hypothesis about how the genome becomes organized into “neighborhoods.”
Gene-editing technology developer Feng Zhang awarded $500,000 Lemelson-MIT Prize
MIT associate professor and member of the Broad Institute and McGovern Institute recognized for commitment to invention, collaboration, and mentorship.