Biology

In humans and most other organisms, a circadian clock governed by light regulates the timing of key aspects of human physiology, by controlling cellular activities such as metabolism and division.

Why working the night shift can pose a cancer risk

New study reveals a link between circadian clock disruption and tumor growth.

July 28, 2016

MIT and Broad Institute postdoc Ilana Brito sampled not only the human microbiome in the remote villages in Fiji she studied, but also the reservoirs of microbes in the community.

Microbiome genes on the move

Largest metagenomic view of the developing world uncovers “mobile genes” that reveal how culture shapes the human microbiome.

July 14, 2016

“It’s intuitive that if a bunch of people are randomly walking around an area, the number of times they bump into each other will be a surrogate of the population density,” says Cameron Musco, an MIT graduate student in electrical engineering and computer science. “What we’re doing is giving a rigorous analysis behind that intuition, and also saying that the estimate is a very good estim...

Exploring networks efficiently

Analysis of ant colony behavior could yield better algorithms for network communication.

July 13, 2016

“How lithium acts on the brain has been this great mystery of psychopharmacology,” says Joshua Meisel, an MIT postdoc and lead author of a new study. “There are hypotheses, but nothing’s been proven.”

New clue to how lithium works in the brain

Biologists find a possible explanation for why the drug helps bipolar patients.

July 7, 2016

Mapping molecular neighborhoods

Associate Professor Ernest Fraenkel uses biological network modeling to identify new targets for disease.

July 5, 2016

A photo of three microfluidic devices filled with food color dyes. The device, about the size of a credit card, is designed to help scientists narrow in on safe ranges of electric fields that might be used to noninvasively treat breast, lung, and other forms of cancer.

New microfluidic device offers means for studying electric field cancer therapy

Low-intensity fields keep malignant cells from spreading, while preserving healthy cells.

July 5, 2016

“This nanoformulation approach allows us to make vaccines against new diseases in only seven days, allowing the potential to deal with sudden outbreaks or make rapid modifications and improvements,” says Daniel Anderson, an associate professor in MIT’s Department of Chemical Engineering and a member of MIT’s Koch Institute for Integrative Cancer Research and Institute for Medical Engineeri...

Engineers design programmable RNA vaccines

Tests in mice show the vaccines work against Ebola, influenza, and a common parasite.

July 4, 2016

Pictured on the left is a spleen; on the right are red blood cells. ““We have presented results showing that the spleen is the main organ that defines the shape of the circulating red blood cells” says Ming Dao, a principal research scientist in MIT’s Department of Materials Science and Engineering.

How the spleen filters blood

Computer model finds slits in the spleen impose a “physical fitness test” on red blood cells.

June 27, 2016

A new report, “Convergence: The Future of Health,” draws on insights from scientists and researchers across academia, industry, and government. The cover of the report is an image of lungs, one of the major sites of metastasis. To help protect the lungs (blue) from this deadly process, bioengineers have created microscopic drug depots (red) to focus the effect of anti-cancer drugs that may hav...

A strategy for “convergence” research to transform biomedicine

Report calls for more integration of physical, life sciences for needed advances in biomedical research.

June 23, 2016

The researchers’ compiler takes as input differential equations and translates them into voltages and current flows across an analog chip.

Analog computing returns

New analog compiler could help enable simulation of whole organs and even organisms.

June 20, 2016

Gene circuits in live cells can perform complex computations

Technique combines analogue and digital processes in engineered cells.

June 3, 2016

Biofuels: Too early or too late?

Professor Kristala Prather engages undergrads in a discussion about the future of biofuels.

May 31, 2016

MIT scientists developed a super-resolution imaging technique, using a combination of multi-colored lasers and mirrors, to visualize very tiny, transient phenomena, such as enzyme clustering on genes.

Scientists illuminate a hidden regulator in gene transcription

New super-resolution technique visualizes important role of short-lived enzyme clusters.

May 25, 2016

In the top image, a neuronal axon (green) forms many synapses, highlighted in purple. The bottom image shows an axon from a fruit fly lacking the Shank protein. In these flies, not as many synapses form, and some of them (indicated by the white arrows) do not fully mature.

Neuroscientists illuminate role of autism-linked gene

Loss of Shank gene prevents neuronal synapses from properly maturing.

May 24, 2016

“When I came to [MIT’s Campus Preview Weekend], I was just blown away by how everybody was so into whatever they were doing,” Maiko Kitaoka says. “I love that atmosphere.”

Maiko Kitaoka finds elegance in unexpected places

Once an aspiring ballerina, the MIT senior now studies the earliest stages of life.