Biological engineering

MIT engineers have designed a system that can repeatedly measure cancer cells as they flow through an array of mass sensors. Once the cells reach the end, they are collected for RNA-sequencing.

Measuring cancer cell “fitness” reveals drug susceptibility

Together, cell growth rate and gene expression shed light on why some tumor cells survive treatment.

November 29, 2018

Six days after treatment with IGF-1 carried by dendrimer nanoparticles (blue), the particles have penetrated through the cartilage of the knee joint.

Potential arthritis treatment prevents cartilage breakdown

Injectable material made of nanoscale particles can deliver arthritis drugs throughout cartilage.

November 28, 2018

Faculty, staff, and graduate students gathered for a luncheon honoring MIT’s 2019 Siebel Scholars.

Sixteen grad students named to the Siebel Scholars class of 2019

MIT students from the fields of bioengineering, business, computer science, and energy science receive the prestigious awards.

November 20, 2018

“The college is our way of building a powerful framework and environment for research and collaborations that involve computing and that are occurring across disciplines," says School of Engineering Dean Anantha P. Chandrakasan, the Vannevar Bush Professor of Electrical Engineering and Computer Science.

Bridge to the future of engineering

The School of Engineering’s faculty leadership weigh in on what the MIT Stephen A. Schwarzman College of Computing will mean for their students and faculty.

November 11, 2018

Armon Sharei, CEO and founder of SQZ Biotech.

Squeezing cells to cure diseases

Startup SQZ Biotech aims to open a new path in immunotherapy with its cell-compressing technique.

October 31, 2018

The researchers (left to right), Joseph Jacobson, a professor of media arts and sciences and head of the Molecular Machines research group, and graduate students in the Media Lab, Pranam Chatterjee and Noah Jakimo.

New CRISPR tool opens up more of the genome for editing

Enzyme can target almost half of the genome’s “ZIP codes” and could enable editing of many more disease-specific mutations.

October 24, 2018

MIT engineers grew these mesenchymal stem cells (red, with blue nuclei) on a surface with mechanical properties similar to those of bone marrow.

Helping blood cells regenerate after radiation therapy

Method boosts differentiation of stem cells into mature blood cell types, may help leukemia and lymphoma patients.

October 24, 2018

A woman in Ghana carries a basket of fish. Local diets and lifestyles have created a remarkable diversity in the human microbiome worldwide.

Studying the hotbed of horizontal gene transfers

Global Microbiome Conservancy research reveals surprising new insights into human gut microbiomes.

October 22, 2018

MIT engineers have developed a sensor that can be used to measure optical and electrical signals in the brain, using MRI.

Monitoring electromagnetic signals in the brain with MRI

Technique could be used to detect light or electrical fields in living tissue.

October 22, 2018

School of Engineering third quarter 2018 awards

Faculty members recognized for excellence via a diverse array of honors, grants, and prizes over the last quarter.

October 19, 2018

MIT biological engineers have devised a way to regulate the expression of RNA once it gets into cells, giving them precise control over the dose of protein that a patient receives, as shown in this conceptual image.

This RNA-based technique could make gene therapy more effective

Biological engineers design RNA circuits that enable precise control over the dose of therapeutic protein a patient receives.

October 16, 2018

Using a computer modeling approach that they developed, MIT biologists identified three different proteins that can bind selectively to each of three similar targets, all members of the Bcl-2 family of proteins.

Computer model offers more control over protein design

New approach generates a wider variety of protein sequences optimized to bind to drug targets.

October 15, 2018

Tyler Jacks (left), head of the Lustgarten Laboratory for Pancreatic Cancer Research at MIT, and Kerri Kaplan, president and chief executive officer of the Lustgarten Foundation, both say they are excited to usher in a new era of pancreatic cancer research.

Progress against pancreatic cancer

Lustgarten Foundation names MIT laboratory to improve understanding and treatment of a deadly disease

October 11, 2018

MIT engineers created this model of the neuromuscular junction using motor neurons derived from ALS patients. The motor neurons (blue) send fibers called neurites (green) toward the muscle fibers (pink).

Testing new drugs with “ALS-on-a-chip”

3-D tissue model replicates the motor neuron connections affected by amyotrophic lateral sclerosis.

October 10, 2018

MIT visiting scholar Padma Lakshmi, the host and executive producer of Bravo’s Top Chef and co-founder of the Endometriosis Foundation of America, speaks to MIT researchers in the lab of Linda Griffith, an MIT School of Engineering Professor of Teaching Innovation, Biological Engineering, and Mechanical Engineering.

A recipe for health

Women’s health advocate, Top Chef host and executive producer, and MIT visiting scholar Padma Lakshmi tours campus, speaks on endometriosis.

October 9, 2018

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