A simple paper test could offer early cancer diagnosis
The new diagnostic, which is based on analysis of urine samples, could also be designed to reveal whether a tumor has metastasized.
Vaccine printer could help vaccines reach more people
The printer generates vaccine-filled microneedle patches that can be stored long-term at room temperature and applied to the skin.
Funding to Daniel Anderson’s lab will advance research on new delivery technology for RNA vaccines and therapies
The global health care company Sanofi is providing $25 million to advance RNA research.
New nanoparticles can perform gene editing in the lungs
Using these RNA-delivery particles, researchers hope to develop new treatments for cystic fibrosis and other lung diseases.
A new control switch could make RNA therapies easier to program
Using this approach, researchers hope to deliver therapeutic RNA molecules selectively to cancer cells or other target cells.
Researchers map brain cell changes in Alzheimer’s disease
Study reveals key cell structures and gene expression changes near amyloid plaques and tau tangles in mouse brain tissue.
Paying it forward
When she’s not analyzing data about her favorite biomolecule, senior Sherry Nyeo focuses on improving the undergraduate experience at MIT.
How Huntington’s disease affects different neurons
A new study identifies cells that are the most vulnerable within a brain structure involved in mood and movement.
New technologies reveal cross-cutting breakdowns in Alzheimer’s disease
“Single-cell profiling” is helping neuroscientists see how disease affects major brain cell types and identify common, potentially targetable pathways.
New CRISPR-based tool inserts large DNA sequences at desired sites in cells
Known as PASTE, the technique holds potential for treating a variety of diseases caused by faulty genes.
When cells’ tiny differences have far-reaching implications
Alex Shalek’s technologies for single-cell RNA profiling can help dissect the cellular bases of complex diseases around the globe.
Robert Langer wins BBVA Foundation Frontiers of Knowledge Award
Institute Professor honored for groundbreaking work in nucleic acid delivery and nanoparticles.
New CRISPR-based map ties every human gene to its function
Jonathan Weissman and collaborators used their single-cell sequencing tool Perturb-seq on every expressed gene in the human genome, linking each to its job in the cell.
Convenience-sized RNA editing
MIT neuroscientists expand CRISPR toolkit with new, compact Cas7-11 enzyme.
3 Questions: Daniel Anderson on the progress of mRNA vaccines
Following the successful development of vaccines against Covid-19, scientists hope to deploy mRNA-based therapies to combat many other diseases.