It takes three to tango: transcription factors bind DNA, protein, and RNA
Whitehead Institute researchers find many transcription factors bind RNA, which fine-tunes their regulation of gene expression, suggesting new therapeutic opportunities.
Whitehead Institute researchers find many transcription factors bind RNA, which fine-tunes their regulation of gene expression, suggesting new therapeutic opportunities.
MIT researchers characterize gene expression patterns for 22,500 brain vascular cells across 428 donors, revealing insights for Alzheimer’s onset and potential treatments.
Study indicates ailing neurons may instigate an inflammatory response from the brain’s microglia immune cells.
Jonathan Weissman and collaborators used their single-cell sequencing tool Perturb-seq on every expressed gene in the human genome, linking each to its job in the cell.
Two MIT faculty members earn funding from the G. Harold and Leila Y. Mathers Foundation.
New genome-editing technique enables rapid analysis of genes mutated in tumors.
NIH-sponsored work to characterize genetic variation in human tissues with roles in diabetes, heart disease, and cancer.
Genetic material hitchhiking in our cells may shape physical traits more than we thought.
Work reveals how a genome-editing tool works to correct errors in the genetic code.
Computer models plus observations of RNA inside a cell help scientists home in on a short list of interesting RNA ‘machines.’
New technique can rapidly turn genes on and off, helping scientists better understand their function.
Improved technique makes it easier to add or delete genes in living cells, with less risk of off-target DNA damage.
MIT biologists reveal how cells control the direction in which the genome is read.