Research update: Genome editing becomes more accurate
Improved technique makes it easier to add or delete genes in living cells, with less risk of off-target DNA damage.
Reading DNA, backward and forward
MIT biologists reveal how cells control the direction in which the genome is read.
Cardiac development needs more than protein-coding genes
Biologists find that long non-coding RNA molecules are necessary to regulate differentiation of embryonic stem cells into cardiac cells.
Editing the genome with high precision
New method allows scientists to insert multiple genes in specific locations, delete defective genes.
Evolution: It’s all in how you splice it
MIT biologists find that alternative splicing of RNA rewires signaling in different tissues and may often contribute to species differences.
Researchers identify biochemical functions for most of the human genome
New map provides a reference for interpreting function of disease-associated regions.
Turning on key enzyme blocks tumor formation
Drug-like molecule restores normal cell metabolism, preventing cancer cells from growing.
Searching genomic data faster
Biologists’ capacity for generating genomic data is increasing more rapidly than computing power. A new algorithm will help them keep up.
Genetic 911: Cells’ emergency systems revealed
Study examines how cells exploit gene sequences to cope with toxic stress.
Getting to the root of genetics
Manolis Kellis uses computational techniques to decipher human disease.
Seeing cancer in three dimensions
Scientists find that the 3-D structure of a cancer cell’s chromosomes plays a big role in which genes get deleted or copied.
Materials research in the Information Age
MIT, Lawrence Berkeley launch new tool to calculate properties of new materials
Scientists unveil tools for rewriting the code of life
New technology from MIT and Harvard can edit DNA at the genome scale, giving cells novel functions.