A new way to regulate gene expression
Biologists uncover an evolutionary trick to control gene expression that reverses the flow of genetic information from RNA splicing back to transcription.
How biomarkers can record and reconstruct climate trends
Scientists reveal the genes and proteins controlling the chemical structures underpinning paleoclimate proxies.
Investigating the rise of oxygenic photosynthesis
EAPS scientists find an alternative explanation for mineral evidence thought to signal the presence of oxygen prior to the Great Oxidation Event.
Continuing a legacy of Antarctic exploration
The Summons Lab compares lipids from Antarctic microbial communities to century-old samples.
![“The major research directions and technology platforms that [my] lab is known for today came out of this process where the students or I had a crazy idea, and then the lab executed on it, with all the twists and turns along the way,” says Paul Blainey, associate professor of biological engineering.](/sites/default/files/styles/term_page__news_article/public/images/201910/MIT-Blainey.jpg?itok=sTavLw_j)
Biological engineer Paul Blainey creates new tools to advance biomedical research
His technology platforms have benefited genomics, diagnostics, and drug screening.
Imaging combined with genetic screening of cells enhances genomic discoveries
New image-based genetic screening method helps researchers identify key regulators of inflammation.
Understanding genetic circuits and genome organization
Assistant professors Pulin Li and Seychelle Vos are investigating how cells become tissues and the proteins that organize DNA.
A comprehensive catalogue of human digestive tract bacteria
Researchers identify nearly 8,000 strains of bacteria, while also clarifying their genetic and metabolic context.
Using CRISPR to program gels with new functions
Smart materials change properties in response to specific DNA sequences; could be used in a variety of devices.
An emerging view of RNA transcription and splicing
Whitehead Institute scientists find chemical modification contributes to trafficking between non-membrane-bound compartments that control gene expression.
Study furthers radically new view of gene control
Along the genome, proteins form liquid-like droplets that appear to boost the expression of particular genes.
A new way to block unwanted genetic transfer
Researchers identify a strategy to prevent mobile genetic elements from breaching the bacterial cell wall.
Speeding up drug discovery for brain diseases
Whitehead Institute team finds drugs that activate a key brain gene; initial tests in cells and mice show promise for rare, untreatable neurodevelopmental disorder.
Neuroscientists identify brain region linked to altered social interactions in autism model
In a mouse model, restoring activity of a specific forebrain region reverses social traits associated with autism.
Uncovering the riches of traditional global medicine
Researchers solve how the kava plant produces its pain-relieving and anti-anxiety molecules, demonstrate an extensible method to scale and optimize production.