Designing the future of metabolic health through tissue-selective drug delivery
Founded by three MIT alumni, Gensaic uses AI-guided protein design to deliver RNA and other therapeutic molecules to specific cells or areas of the body.
Pills that communicate from the stomach could improve medication adherence
MIT engineers designed capsules with biodegradable radio frequency antennas that can reveal when the pill has been swallowed.
A new patch could help to heal the heart
MIT engineers developed a programmable drug-delivery patch that can promote tissue healing and blood vessel regrowth following a heart attack.
New nanoparticles stimulate the immune system to attack ovarian tumors
Targeted particles carrying the cytokine IL-12 can jump-start T cells, allowing them to clear tumors while avoiding side effects.
“Bottlebrush” particles deliver big chemotherapy payloads directly to cancer cells
Outfitted with antibodies that guide them to the tumor site, the new nanoparticles could reduce the side effects of treatment.
How AI could speed the development of RNA vaccines and other RNA therapies
MIT engineers used a machine-learning model to design nanoparticles that can deliver RNA to cells more efficiently.
Adhesive inspired by hitchhiking sucker fish sticks to soft surfaces underwater
The mechanical system could be used to deliver drugs in the GI tract or monitor aquatic environments.
Implantable device could save diabetes patients from dangerously low blood sugar
The new implant carries a reservoir of glucagon that can be stored under the skin and deployed during an emergency — with no injections needed.
MIT engineers uncover a surprising reason why tissues are flexible or rigid
Watery fluid between cells plays a major role, offering new insights into how organs and tissues adapt to aging, diabetes, cancer, and more.
Once-a-week pill for schizophrenia shows promise in clinical trials
The ingestible capsule forms a drug depot in the stomach, gradually releasing its payload and eliminating the need for patients to take medicine every day.
Particles carrying multiple vaccine doses could reduce the need for follow-up shots
MIT engineers designed polymer microparticles that can deliver vaccines at predetermined times after injection.
Engineers develop a way to mass manufacture nanoparticles that deliver cancer drugs directly to tumors
Scaling up nanoparticle production could help scientists test new cancer treatments.
Engineers develop a better way to deliver long-lasting drugs
With tinier needles and fewer injections, the approach may enable new options for long-term delivery of contraceptives or treatments for diseases such as HIV.
Designing better ways to deliver drugs
Graduate student and MathWorks Fellow Louis DeRidder is developing a device to make chemotherapy dosing more accurate for individual patients.
Creating innovative health solutions for individuals and populations
Physician and engineer Giovanni Traverso found an early passion for molecular genetics, leading to an interdisciplinary career helping others.