In a surprising discovery, scientists find tiny loops in the genomes of dividing cells
Enabled by a new high-resolution mapping technique, the findings overturn a long-held belief that the genome loses its 3D structure when cells divide.
Enabled by a new high-resolution mapping technique, the findings overturn a long-held belief that the genome loses its 3D structure when cells divide.
MIT researchers have dramatically lowered the error rate of prime editing, a technique that holds potential for treating many genetic disorders.
Cache DNA has developed technologies that can preserve biomolecules at room temperature to make storing and transporting samples less expensive and more reliable.
The findings may redefine how cell identity is established and enable the creation of more sophisticated engineered tissues.
The longtime MIT professor and Nobel laureate was a globally respected researcher, academic leader, and science policy visionary who guided the careers of generations of scientists.
Professor Caroline Uhler discusses her work at the Schmidt Center, thorny problems in math, and the ongoing quest to understand some of the most complex interactions in biology.
Researchers develop a fast-acting, cell-permeable protein system to control CRISPR-Cas9, reducing off-target effects and advancing gene therapy.
Electrodes coated with DNA could enable inexpensive tests with a long shelf-life, which could detect many diseases and be deployed in the doctor’s office or at home.
Researchers redesign a compact RNA-guided enzyme from bacteria, making it an efficient editor of human DNA.
Pathways involved in DNA repair and other cellular functions could contribute to the development of Alzheimer’s.
Trained with a joint understanding of protein and cell behavior, the model could help with diagnosing disease and developing new drugs.
Two meters of DNA is crammed into the nucleus of every human cell. Bin Zhang wants to know how gene expression works in this minuscule space.
MIT associate professor recognized for exceptional distinction in teaching, research, and service at MIT.
CAMP4 Therapeutics is targeting regulatory RNA, whose role in gene expression was first described by co-founder and MIT Professor Richard Young.
Stuart Levine ’97, director of MIT’s BioMicro Center, keeps departmental researchers at the forefront of systems biology.