A comprehensive map of the SARS-CoV-2 genome
MIT researchers have determined the virus’ protein-coding gene set and analyzed new mutations’ likelihood of helping the virus adapt.
Biologists discover a trigger for cell extrusion
Study suggests this process for eliminating unneeded cells may also protect against cancer.
An on-off switch for gene editing
New, reversible CRISPR method can control gene expression while leaving underlying DNA sequence unchanged.
Study: One enzyme dictates cells’ response to a probable carcinogen
Varying levels of a DNA repair enzyme can lead to very different outcomes after exposure to NDMA.
MIT team improving gene therapies wins Sloan health care prize
Kano Therapeutics was one of eight finalists to pitch at the virtual competition.
Epigenomic map reveals circuitry of 30,000 human disease regions
Analysis reveals genetic control elements that are linked to hundreds of human traits.
Catching cancer in the act
Using CRISPR technology, researchers are tracking the lineage of individual cancer cells as they proliferate and metastasize in real-time.
Why cancer cells waste so much energy
MIT study sheds light on the longstanding question of why cancer cells get their energy from fermentation.
Neuroscientists discover a molecular mechanism that allows memories to form
Modifications to chromosomes in “engram” neurons control the encoding and retrieval of memories.
Scientists discover new rules about “runaway” transcription
Findings related to bacterial gene expression overturn fundamental assumptions about basic biological pathways.
Gene-controlling mechanisms play key role in cancer progression
Study finds “epigenomic” alterations evolve as lung tumors become more aggressive and metastasize.
3 Questions: Ibrahim Cissé on using physics to decipher biology
A physicist employs super-resolution microscopy to peer inside living cells and witness never-before-seen phenomena.
3 Questions: Seychelle Vos on detangling DNA
An unconventional geneticist uses cryogenic electron microscopy and crystallography to understand gene expression and cell fate.
Nature-inspired CRISPR enzymes for expansive genome editing
Applied computational biology discoveries vastly expand the range of CRISPR’s access to DNA sequences.
SHERLOCK-based one-step test provides rapid and sensitive Covid-19 detection
New CRISPR-based research tool delivers results in an hour; researchers share protocol and kits to advance research and move toward clinical validation.