Topic
DNA
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Revising the textbook on introns
Whitehead Institute researchers uncover a group of introns in yeast that possess surprising stability and function.
January 16, 2019 -
DNA design that anyone can do
Computer program can translate a free-form 2-D drawing into a DNA structure.
January 3, 2019 -
Engineering "capture compounds" to probe cell growth
Researchers develop a method to investigate how bacteria respond to starvation and to identify which proteins bind to the “magic spot” — ppGpp.
December 17, 2018 -
Tracking the footprints of protein synthesis
Researchers refine a method to quantify protein production, show that the precision with which bacteria and eukaryotes tune their gene expression is remarkably similar.
December 14, 2018 -
Team invents method to shrink objects to the nanoscale
It’s not quite the Ant-Man suit, but the system produces 3-D structures one thousandth the size of the originals.
December 13, 2018 -
The long and short of CDK12
A new study linking RNA processing to DNA repair may open new avenues to cancer therapy.
November 30, 2018 -
New CRISPR tool opens up more of the genome for editing
Enzyme can target almost half of the genome’s “ZIP codes” and could enable editing of many more disease-specific mutations.
October 24, 2018 -
This RNA-based technique could make gene therapy more effective
Biological engineers design RNA circuits that enable precise control over the dose of therapeutic protein a patient receives.
October 16, 2018 -
Taming “information hazards” in synthetic biology research
Cryptography techniques to screen synthetic DNA could help prevent the creation of dangerous pathogens, argues Professor Kevin Esvelt.
October 4, 2018 -
Detangling DNA replication
Researchers identify an essential protein that helps enzymes relax overtwisted DNA so each strand can be copied during cell division.
September 17, 2018 -
Tissue architecture affects chromosome segregation
Biologists discover that the environment surrounding a cell plays an integral role in its ability to accurately segregate its chromosomes.
August 23, 2018 -
Ankur Jain joins Whitehead Institute and the Department of Biology
Biophysicist will investigate the biology of RNA aggregation.
June 11, 2018 -
Decoding RNA-protein interactions
Scientists leverage one step, unbiased method to characterize the binding preferences of more than 70 human RNA-binding proteins.
June 7, 2018 -
Untangling DNA knots
Chemical engineers discover how to control knots that form in DNA molecules.
May 3, 2018 -
Countering mitochondrial stress
Scientists discover a pathway that monitors a protein import into mitochondria and elicits a cellular response when the process goes awry.
April 13, 2018 -
Scientists find different cell types contain the same enzyme ratios
New discovery suggests that all life may share a common design principle.
March 29, 2018 -
Timothy Lu seeks to combat disease by reprogramming biological systems
Synthetic biologist hopes to develop treatments for cancer and other diseases.
March 4, 2018 -
Scientists deliver high-resolution glimpse of enzyme structure
New finding suggests differences in how humans and bacteria control production of DNA’s building blocks.
February 20, 2018 -
Researchers advance CRISPR-based tool for diagnosing disease
With SHERLOCK, a strip of paper can now indicate presence of pathogens, tumor DNA, or any genetic signature of interest.
February 15, 2018 -
Study: Fragile X syndrome neurons can be restored
Whitehead Institute researchers are using a modified CRISPR/Cas9-guided activation strategy to investigate the most frequent cause of intellectual disability in males.
February 15, 2018