MIT engineers develop electrochemical sensors for cheap, disposable diagnostics
Electrodes coated with DNA could enable inexpensive tests with a long shelf-life, which could detect many diseases and be deployed in the doctor’s office or at home.
Rationale engineering generates a compact new tool for gene therapy
Researchers redesign a compact RNA-guided enzyme from bacteria, making it an efficient editor of human DNA.
Scientists discover potential new targets for Alzheimer’s drugs
Pathways involved in DNA repair and other cellular functions could contribute to the development of Alzheimer’s.
With AI, researchers predict the location of virtually any protein within a human cell
Trained with a joint understanding of protein and cell behavior, the model could help with diagnosing disease and developing new drugs.
Using AI to explore the 3D structure of the genome
Two meters of DNA is crammed into the nucleus of every human cell. Bin Zhang wants to know how gene expression works in this minuscule space.
Anders Sejr Hansen named Edgerton Award winner
MIT associate professor recognized for exceptional distinction in teaching, research, and service at MIT.
Restoring healthy gene expression with programmable therapeutics
CAMP4 Therapeutics is targeting regulatory RNA, whose role in gene expression was first described by co-founder and MIT Professor Richard Young.
At the core of problem-solving
Stuart Levine ’97, director of MIT’s BioMicro Center, keeps departmental researchers at the forefront of systems biology.
An ancient RNA-guided system could simplify delivery of gene editing therapies
The programmable proteins are compact, modular, and can be directed to modify DNA in human cells.
A protein from tiny tardigrades may help cancer patients tolerate radiation therapy
When scientists stimulated cells to produce a protein that helps “water bears” survive extreme environments, the tissue showed much less DNA damage after radiation treatment.
AI system predicts protein fragments that can bind to or inhibit a target
FragFold, developed by MIT Biology researchers, is a computational method with potential for impact on biological research and therapeutic applications.
Professor Anthony Sinskey, biologist, inventor, entrepreneur, and Center for Biomedical Innovation co-founder, dies at 84
Colleagues remember the longtime MIT professor as a supportive, energetic collaborator who seemed to know everyone at the Institute.
MIT biologists discover a new type of control over RNA splicing
They identified proteins that influence splicing of about half of all human introns, allowing for more complex types of gene regulation.
With generative AI, MIT chemists quickly calculate 3D genomic structures
A new approach, which takes minutes rather than days, predicts how a specific DNA sequence will arrange itself in the cell nucleus.
An abundant phytoplankton feeds a global network of marine microbes
New findings illuminate how Prochlorococcus’ nightly “cross-feeding” plays a role in regulating the ocean’s capacity to cycle and store carbon.