Topic
DNA
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New gene-editing system precisely inserts large DNA sequences into cellular DNA
Researchers identify and develop new CRISPR-associated transposase system for targeted integration of DNA, adding key capabilities to gene-editing technology.
June 12, 2019 -
Drug makes tumors more susceptible to chemo
Compound that knocks out a DNA repair pathway enhances cisplatin treatment and helps prevent drug-resistance.
June 6, 2019 -
A “biomultimeter” lets scientists measure RNA and protein production in real-time
Fluorescent tagging system can expedite the process of designing genes and personalizing medicine.
May 20, 2019 -
The evolving definition of a gene
Professor Gerald Fink, a pioneer in the field of genetics, delivers the annual Killian Lecture.
April 5, 2019 -
Academic institutions grant commercial license for CRISPR-based SHERLOCK diagnostic technology in developed world
Rights are protected for broad use in developing world and for public health needs.
March 21, 2019 -
An easier way to engineer plants
MIT-led team uses nanoparticles to deliver genes into plant chloroplasts.
February 25, 2019 -
Why too much DNA repair can injure tissue
Overactive repair system promotes cell death following DNA damage by certain toxins, study shows.
February 12, 2019 -
Biologists answer fundamental question about cell size
The need to produce just the right amount of protein is behind the striking uniformity of sizes.
February 7, 2019 -
Scientists engineer new CRISPR platform for DNA targeting
CRISPR team harnesses new Cas12b enzyme for use in eukaryotic cells, adding to the CRISPR toolbox.
January 22, 2019 -
Revising the textbook on introns
Whitehead Institute researchers uncover a group of introns in yeast that possess surprising stability and function.
January 16, 2019 -
DNA design that anyone can do
Computer program can translate a free-form 2-D drawing into a DNA structure.
January 3, 2019 -
Engineering "capture compounds" to probe cell growth
Researchers develop a method to investigate how bacteria respond to starvation and to identify which proteins bind to the “magic spot” — ppGpp.
December 17, 2018 -
Tracking the footprints of protein synthesis
Researchers refine a method to quantify protein production, show that the precision with which bacteria and eukaryotes tune their gene expression is remarkably similar.
December 14, 2018 -
Team invents method to shrink objects to the nanoscale
It’s not quite the Ant-Man suit, but the system produces 3-D structures one thousandth the size of the originals.
December 13, 2018 -
The long and short of CDK12
A new study linking RNA processing to DNA repair may open new avenues to cancer therapy.
November 30, 2018 -
New CRISPR tool opens up more of the genome for editing
Enzyme can target almost half of the genome’s “ZIP codes” and could enable editing of many more disease-specific mutations.
October 24, 2018 -
This RNA-based technique could make gene therapy more effective
Biological engineers design RNA circuits that enable precise control over the dose of therapeutic protein a patient receives.
October 16, 2018 -
Taming “information hazards” in synthetic biology research
Cryptography techniques to screen synthetic DNA could help prevent the creation of dangerous pathogens, argues Professor Kevin Esvelt.
October 4, 2018 -
Detangling DNA replication
Researchers identify an essential protein that helps enzymes relax overtwisted DNA so each strand can be copied during cell division.
September 17, 2018 -
Tissue architecture affects chromosome segregation
Biologists discover that the environment surrounding a cell plays an integral role in its ability to accurately segregate its chromosomes.
August 23, 2018