Understanding genetic circuits and genome organization
Assistant professors Pulin Li and Seychelle Vos are investigating how cells become tissues and the proteins that organize DNA.
To divide or not to divide?
Whitehead Institute team reveals molecular program that controls cells’ capacity for division.
Neurons’ “antennae” are unexpectedly active in neural computation
Tiny, branching extensions called dendrites may be more than just passive information-carriers, study finds.
Biologists find a way to boost intestinal stem cell populations
Study suggests that stimulating stem cells may protect the gastrointestinal tract from age-related disease.
Acoustic waves can monitor stiffness of living cells
Technique sheds light on cells’ health and development; may be useful for precision medicine.
Biologists answer fundamental question about cell size
The need to produce just the right amount of protein is behind the striking uniformity of sizes.
Activating a new understanding of gene regulation
Study reveals the role of the activation domain, a part of transcription factors previously shrouded in mystery.
Squeezing cells to cure diseases
Startup SQZ Biotech aims to open a new path in immunotherapy with its cell-compressing technique.
Testing new drugs with “ALS-on-a-chip”
3-D tissue model replicates the motor neuron connections affected by amyotrophic lateral sclerosis.
Scientists alter membrane proteins to make them easier to study
By making hydrophobic sections water-soluble, researchers hope to learn more about protein structures.
Charting a path to better cell models of the intestine
Researchers generate an intestinal cell mimic that can be harnessed in studies of diseases such as inflammatory bowel disease.
Structure of key growth regulator revealed
Researchers identify the molecular structure of the GATOR1 protein complex, which regulates growth signals in human cells, using cryo-electron microscopy.
Cholesterol helps flu virus escape through host cell’s membrane
Study could shed light on how many other proteins bind with membrane cholesterol.
Laura Kiessling wins Tetrahedron Prize for Creativity in Organic Chemistry
Professor of chemistry is the first woman to win the prestigious prize, awarded annually for creativity in organic chemistry or bioorganic and medicinal chemistry.