Astrocyte cells critical for learning skilled movements
When astrocyte function is disrupted, neurons in the brain’s motor cortex struggle to execute and refine motion, a new study in mice shows.
Bacterial injection system delivers proteins in mice and human cells
With further development, the programmable system could be used in a range of applications including gene and cancer therapies.
How cell mechanics influences everything
Ming Guo seeks connections between a cell’s physical form and its biological function, which could illuminate ways to halt abnormal cell growth.
3 Questions: Cullen Buie on a new era for cell therapies
The associate professor of MechE reflects on how his company, Kytopen, has grown and shifted focus in developing safer immunotherapies.
“Spleen-on-a-chip” yields insight into sickle cell disease
With this microfluidic device, researchers modeled how sickled blood cells clog the spleen’s filters, leading to a potentially life-threatening condition.
2022-23 Takeda Fellows: Leveraging AI to positively impact human health
New fellows are working on health records, robot control, pandemic preparedness, brain injuries, and more.
Enzyme “atlas” helps researchers decipher cellular pathways
Biologists have mapped out more than 300 protein kinases and their targets, which they hope could yield new leads for cancer drugs.
Scientists discover a new way of sharing genetic information in a common ocean microbe
Prochlorococcus, the world’s most abundant photosynthetic organism, reveals a gene-transfer mechanism that may be key to its abundance and diversity.
Self-assembling proteins can store cellular “memories”
Using these engineered proteins, researchers can record histories that reveal when certain genes are activated or how cells respond to a drug.
New tool can assist with identifying carbohydrate-binding proteins
Groundbreaking research can help alleviate the challenges affiliated with studying carbohydrates.
Silent synapses are abundant in the adult brain
These immature connections may explain how the adult brain is able to form new memories and absorb new information.
Scientists unveil the functional landscape of essential genes
Researchers harness new pooled, image-based screening method to probe the functions of over 5,000 essential genes in human cells.
Ocean microbes get their diet through a surprising mix of sources, study finds
Up to one-third of the carbon consumed by Prochlorococcus may come from sources other than photosynthesis.
Nanosensors target enzymes to monitor and study cancer
By analyzing enzyme activity at the organism, tissue, and cellular scales, new sensors could provide new tools to clinicians and cancer researchers.
A “door” into the mitochondrial membrane
Study finds the protein MTCH2 is responsible for shuttling various other proteins into the membrane of mitochondria. The finding could have implications for cancer treatments and MTCH2-linked conditions.