Study finds cell memory can be more like a dimmer dial than an on/off switch
The findings may redefine how cell identity is established and enable the creation of more sophisticated engineered tissues.
A comprehensive cellular-resolution map of brain activity
An international collaboration of neuroscientists, including MIT Professor Ila Fiete, developed a brain-wide map of decision-making at cellular resolution in mice.
3 Questions: On biology and medicine’s “data revolution”
Professor Caroline Uhler discusses her work at the Schmidt Center, thorny problems in math, and the ongoing quest to understand some of the most complex interactions in biology.
Locally produced proteins help mitochondria function
Researchers developed an approach to study where proteins get made, and characterized proteins produced near mitochondria, gaining potential insights into mitochondrial function and disease.
Imaging tech promises deepest looks yet into living brain tissue at single-cell resolution
By combining several cutting-edge imaging technologies, a new microscope system could enable unprecedentedly deep and precise visualization of metabolic and neuronal activity, potentially even in humans.
Mapping cells in time and space: New tool reveals a detailed history of tumor growth
Researchers developed a tool to recreate cells’ family trees. Comparing cells’ lineages and locations within a tumor provided insights into factors shaping tumor growth.
How to more efficiently study complex treatment interactions
A new approach for testing multiple treatment combinations at once could help scientists develop drugs for cancer or genetic disorders.
Connect or reject: Extensive rewiring builds binocular vision in the brain
A first-of-its-kind study in mice shows neurons add and shed synapses at a frenzied pace during development to integrate visual signals from the two eyes.
New AI system uncovers hidden cell subtypes, boosts precision medicine
CellLENS reveals hidden patterns in cell behavior within tissues, offering deeper insights into cell heterogeneity — vital for advancing cancer immunotherapy.
New method combines imaging and sequencing to study gene function in intact tissue
The approach collects multiple types of imaging and sequencing data from the same cells, leading to new insights into mouse liver biology.
MIT engineers uncover a surprising reason why tissues are flexible or rigid
Watery fluid between cells plays a major role, offering new insights into how organs and tissues adapt to aging, diabetes, cancer, and more.
When Earth iced over, early life may have sheltered in meltwater ponds
Modern-day analogs in Antarctica reveal ponds teeming with life similar to early multicellular organisms.
Technique rapidly measures cells’ density, reflecting health and developmental state
The method could help predict whether immunotherapies will work in a patient or how a tumor will respond to drug treatment.
With AI, researchers predict the location of virtually any protein within a human cell
Trained with a joint understanding of protein and cell behavior, the model could help with diagnosing disease and developing new drugs.
A new computational framework illuminates the hidden ecology of diseased tissues
The MESA method uses ecological theory to map cellular diversity and spatial patterns in tissues, offering new insights into disease progression.