A new method to enhance effectiveness of cartilage repair therapy
SMART researchers find mesenchymal stromal cells are an attractive alternative to current costly, time-intensive treatments.
A new framework to efficiently screen drugs
Novel method to scale phenotypic drug screening drastically reduces the number of input samples, costs, and labor required to execute a screen.
Jane-Jane Chen: A model scientist who inspires the next generation
A research scientist and internationally recognized authority in the field of blood cell development reflects on 45 years at MIT.
A new way to reprogram immune cells and direct them toward anti-tumor immunity
MIT scientists’ discovery yields a potent immune response, could be used to develop a potential tumor vaccine.
A new way to miniaturize cell production for cancer treatment
A chip the size of a pack of cards uses fewer resources and a smaller footprint than existing automated manufacturing platforms and could lead to more affordable cell therapy manufacturing.
What happens during the first moments of butterfly scale formation
New findings could help engineers design materials for light and heat management.
“Rosetta Stone” of cell signaling could expedite precision cancer medicine
An atlas of human protein kinases enables scientists to map cell signaling pathways with unprecedented speed and detail.
Improving drug development with a vast map of the immune system
Immunai’s founders were researchers at MIT when they launched their company to help predict how patients will respond to new treatments.
Unlocking mRNA’s cancer-fighting potential
MIT spinout Strand Therapeutics has developed a new class of mRNA molecules that can sense where they are in the body, for more targeted and powerful treatments.
Study: Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps
Single-cell gene expression patterns in the brain, and evidence from follow-up experiments, reveal many shared cellular and molecular similarities that could be targeted for potential treatment.
Exploring the cellular neighborhood
Software allows scientists to model shapeshifting proteins in native cellular environments.
How sensory gamma rhythm stimulation clears amyloid in Alzheimer’s mice
Study finds stimulating a key brain rhythm with light and sound increases peptide release from interneurons, driving clearance of an Alzheimer’s protein.
Deciphering the cellular mechanisms behind ALS
Professor Ernest Fraenkel has decoded fundamental aspects of Huntington’s disease and glioblastoma, and is now using computation to better understand amyotrophic lateral sclerosis.
Scientists develop a low-cost device to make cell therapy safer
A plastic microfluidic chip can remove some risky cells that could potentially become tumors before they are implanted in a patient.
Blood cell family trees trace how production changes with aging
Jonathan Weissman and collaborators developed a tool to reconstruct human cell family trees, revealing how blood cell production changes in old age.