Media Outlet: Science Publication Date: March 6, 2024 Description: Bingxu Liu PhD '23 speaks with Science reporter Christie Wilcox about his work studying STING, an immune protein that plays a key role in defending the human body against viruses, bacteria, and tumors. “STING is actually one of the most promising cancer immunotherapy targets,” explains Wilcox. “If you activate the STING pathway, it triggers a very strong immune response. But when it’s too strong, it can actually kill your T cells. Initial evidence suggest that T cells die because of some ion impact. Which begs the question: Can we just use STING to activate some parts of the immune response, like interferon, but also block the ion flow [that’s harming T cells]?” Full story via Science → Related Topics Alumni/aeCancerCellsResearchSchool of ScienceBiology