Prof. Regina Barzilay speaks with WBUR’s Priyanka Dayal McCluskey about her work developing an AI risk detection tool that can analyze mammogram images and help predict risk of breast cancer before it happens or spreads. Barzilay, who describes the tool as a hi-tech weather forecast for breast health, notes that: “We really need to have tools that can help, rather than just staring at an image and trying to guess.”
Sybil, a new AI tool developed by researchers from MIT and Mass General Brigham Cancer Institute, “analyzes a single CT scan and generates a risk score predicting the likelihood of developing lung cancer over a period of up to six years,” reports Ivan Rodriguez for WCVB-TV. “In 2023, researchers reported that Sybil achieved an accuracy rate of 86% to 94% in distinguishing high-risk patients from low-risk patients within a year.”
Reporting for CNN, Caleb Hellerman spotlights how MIT computer scientists developed an AI program called Sybil that can “‘look’ at a single CT scan and generate a ‘risk score’ corresponding to the likelihood of the person developing cancer over any period up to six years.”
Prof. Angela Belcher and Prof. Sangeeta Bhatia chat with Edgar B. Herwick III of GBH’s The Curiosity Desk about their efforts aimed at improving diagnostics for ovarian cancer. “We now know that ovarian cancer doesn’t originate in the ovaries. About 80% of the time, ovarian cancer starts in the fallopian tubes, but it can sit there as this precancerous lesion,” explains Belcher. “There’s new technologies that can be invented and developed to detect it much earlier, because if it’s detected earlier…there’s such an opportunity to make an impact.”
Researchers at MIT have developed a wearable breast cancer ultrasound device that could be used to detect breast cancer earlier, reports Amerigo Allegretto for AuntMinnie.com. “The device can image as deep as 15 cm into breast tissue and can image the entire breast from two or three locations,” explains Allegretto. “The team described the technology as an end-to-end system ultrasound architecture consisting of a novel sparse array geometry and a codesigned data acquisition system.”
Prof. Giovanni Traverso and his colleagues developed a new technique that could one day be used to help protect cancer patients from the side effects of radiation therapy, reports Elie Dolgin for Science. The researchers found that providing brief pulses of a protein called “damage suppressor,” or Dsup could “shield injected tissues from radiation. They also found no evidence of acute toxicity with repeat doses, which bodes well for short-term use in clinical settings—for example, to protect nearby tissues during radiation treatment for a cancer,” Dolgin explains.
Forbes reporter Craig Smith spotlights Prof. Regina Barzilay for her work using her personal health experience to develop transformative medical technology. In response to her breast cancer diagnosis, Barzilay “developed a deep learning model that analyzes mammography images to predict breast cancer risk up to five years in advance,” writes Smith.
Early research from MIT scientists suggests that over time a high-fat diet can impact the liver in a way that may raise the risk of cancer. “When the liver repeatedly processes large amounts of fat, its main working cells stop focusing on breaking down nutrients and filtering toxins,” writes Deirdre Bardolf for Fox News. “They revert to a more primitive state to help them endure the strain of a fatty diet, a shift researchers associate with tumorigenesis, the process by which cancer can develop.”
Prof. Canan Dagdeviren speaks with Bloomberg Businessweek Daily reporters Carol Massar and Tim Stenovec about her work developing conformable ultrasound technology aimed at enabling earlier breast cancer detection. “This technology can be a part of your personal bra, and you can wear it and while drinking your coffee within seconds, it can tell you [about] any anomaly with pinpoint accuracy,” Dagdeviren explains.
WBUR reporter Rachell Sanchez-Smith spotlights two health tech devices being developed by Prof. Yoel Fink and Prof. Canan Dağdeviren, respectively, that aim to “give the wearers — and their doctors — a clearer picture of their overall health.” Fink has created “a thread capable of storing data, running artificial intelligence algorithms, sensing motion and sound, and communication through Bluetooth,” while Dağdeviren’s wearable ultrasound scanner can be used to make breast cancer screening “more comfortable and more accurate,” explains Sanchez-Smith.
Strand Therapeutics, co-founded Jake Becraft PhD '19, has developed a programmable drug that could one day shrink tumors in cancer patients, reports Amy Feldman for Forbes. “It shocked even us,” says Becraft. “You hope something happens, but you don’t expect to see a huge response because these patients have already proven to have cancers so resistant to treatment.”
Writing for GBH, graduate students and alumni Jessica Chomik-Morales, Sarah Akaaboune, Mackenzie White '25, Celina Zhao '24, SM '25, spotlight the Dana-Farber mobile Mammogram Van. “The unit meets women where they live and work, offering care in the languages they speak,” they write. “By bringing screenings to neighborhoods with large Asian and other minority populations, the van shows how community-based, culturally responsive care can reduce disparities and improve access to critical health resources.”
Prof. Canan Dagdeviren speaks with NBC Boston reporter Priscilla Casper about her work developing a wearable ultrasound scanner that can be used for early breast cancer detection, with the goal of empowering “women to monitor their own bodies, on their own time and in the comfort of their own home.” Dagdeviren explains that “our hope [is to] collect a lot of data and use AI to predict what will happen to breast tissue over time.”
Chronicle visits MIT to learn more about how the Institute “nurtures groundbreaking efforts, reminding us that creativity and science thrive together, inspiring future advancements in engineering, medicine, and beyond.” Prof. Julien de Wit and Research Scientist Artem Burdanov discuss their planetary defense efforts aimed at identifying small asteroids that could pose a threat to Earth, and Prof. Canan Dağdeviren demonstrates her work developing ultrasound devices to detect the earliest stages of breast cancer. Host Anthony Everett notes that: “Big ideas have a way of breaking out of conventional boundaries, just part of what makes MIT one giant laboratory of groundbreaking ideas."
Scientific American reporter Nic Flemming spotlights research by Prof. Ömer Yilmaz and his team, which explores the impact of fasting on intestinal stem cells. “Both caloric restriction and fasting improved intestinal stem-cell activity and health, but the mechanisms involved are very different,” says Yilmaz.