Study models how ketamine’s molecular action leads to its effects on the brain
New research addresses a gap in understanding how ketamine’s impact on individual neurons leads to pervasive and profound changes in brain network function.
Picower Institute for Learning and Memory
Understanding why autism symptoms sometimes improve amid fever
With support from The Marcus Foundation, an MIT neuroscientist and a Harvard Medical School immunologist will study the “fever effect” in an effort to devise therapies that mimic its beneficial effects.
To understand cognition — and its dysfunction — neuroscientists must learn its rhythms
A new framework describes how thought arises from the coordination of neural activity driven by oscillating electric fields — a.k.a. brain “waves” or “rhythms.”
MIT tops among single-campus universities in US patents granted
For 10th consecutive year, the Institute ranks No. 2 among all colleges and No. 1 among colleges with one main campus, underlying the impact of innovation and critical role of technology transfer.
Study: Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps
Single-cell gene expression patterns in the brain, and evidence from follow-up experiments, reveal many shared cellular and molecular similarities that could be targeted for potential treatment.
How sensory gamma rhythm stimulation clears amyloid in Alzheimer’s mice
Study finds stimulating a key brain rhythm with light and sound increases peptide release from interneurons, driving clearance of an Alzheimer’s protein.
A noninvasive treatment for “chemo brain”
Stimulating gamma brain waves may protect cancer patients from memory impairment and other cognitive effects of chemotherapy.
School of Science announces 2024 Infinite Expansion Awards
Nine postdocs and research scientists honored for contributions to the Institute.
Simons Center’s collaborative approach propels autism research, at MIT and beyond
Team-based targeted projects, multi-mentor fellowships ensure that scientists studying social cognition, behavior, and autism integrate multiple perspectives and approaches to pressing questions.
Creating new skills and new connections with MIT’s Quantitative Methods Workshop
More than 80 students and faculty from a dozen collaborating institutions became immersed at the intersection of computation and life sciences and forged new ties to MIT and each other.
Evidence that gamma rhythm stimulation can treat neurological disorders is emerging
Researchers survey a broadening landscape of studies showing what’s known, and what remains to be found, about the therapeutic potential of noninvasive sensory, electrical, or magnetic stimulation of gamma brain rhythms.
Study reveals a universal pattern of brain wave frequencies
Across mammalian species, brain waves are slower in deep cortical layers, while superficial layers generate faster rhythms.
Nanoparticle-delivered RNA reduces neuroinflammation in lab tests
MIT researchers find that in mice and human cell cultures, lipid nanoparticles can deliver a potential therapy for inflammation in the brain, a prominent symptom in Alzheimer’s.
How a mutation in microglia elevates Alzheimer’s risk
A new study finds that microglia with mutant TREM2 protein reduce brain circuit connections, promote inflammation, and contribute to Alzheimer’s pathology in other ways.
Elly Nedivi receives 2023 Kreig Cortical Kudos Discoverer Award
The neuroscientist is recognized for her ongoing work to understand molecular and cellular mechanisms that enable the brain to adapt to experience.