Neural vulnerability in Huntington’s disease tied to release of mitochondrial RNA
Unique survey of gene expression by cell type in humans and mice reveals several deficits affecting the most vulnerable neurons.
Broad Institute of MIT and Harvard
Engineers use “DNA origami” to identify vaccine design rules
In lab tests, virus-like DNA structures coated with viral proteins provoke a strong immune response in human B cells.
Bringing the predictive power of artificial intelligence to health care
The startup ClosedLoop has created a platform of predictive models to help organizations improve patient care.
Research highlights immune molecule’s complex role in Huntington’s disease
Knocking out the immune cytokine IL-6 exacerbates symptoms in HD model mice, affects neural connection genes.
Scientists find a new way to reverse symptoms of Fragile X
Drug compound, tested in mice, could be effective in treating the leading heritable cause of intellectual disability and autism.
SHERLOCK-based one-step test provides rapid and sensitive Covid-19 detection
New CRISPR-based research tool delivers results in an hour; researchers share protocol and kits to advance research and move toward clinical validation.
Three from MIT elected to the National Academy of Sciences for 2020
Faculty members Abhijit Banerjee, Bonnie Berger, and Roger Summons elected by peers for outstanding contributions to research.
CRISPR-based diagnostic chips perform thousands of tests simultaneously to detect viruses
Diagnostic platform CARMEN combines microfluidics with CRISPR-based detection technology SHERLOCK, and could one day be used for public health efforts.
Alex Shalek wins Edgerton Faculty Award
Professor of chemistry and IMES core member is recognized for his leadership and pioneering spirit.
Jim Collins receives funding to harness AI for drug discovery
The Audacious Project commitment will support the development of new classes of antibiotics to treat the world’s deadliest bacterial pathogens.
Researchers identify cells likely targeted by Covid-19 virus
Study finds specific cells in the lungs, nasal passages, and intestines that are more susceptible to infection.
Pioneering researcher Jonathan Weissman joins Whitehead Institute and MIT
Globally respected cell biologist will be the Whitehead Institute’s inaugural Landon T. Clay Professor of Biology and a professor of biology at MIT.
3 Questions: Renae Irving on creating supportive learning environments for middle- and high-school students
Molecular biology researcher and MIT alumna is an Office of Engineering Outreach Programs (OEOP) instructor.
Historic migration patterns are written in Americans' DNA
Genetic, geographic, and demographic data from more than 30,000 Americans reveal more genetic diversity within ancestry groups than previously thought.
Not your average science classroom
MIT student volunteers host fifth annual Northeast Regional Middle School Science Bowl for over 100 middle schoolers.