New method could improve manufacturing of gene-therapy drugs
Selective crystallization can greatly improve the purity, selectivity, and active yield of viral vector-based gene therapy drugs, MIT study finds.
Designing better, longer-lasting medicines
Adding amino acids to certain protein-based medications can improve stability and effectiveness. New MIT research demonstrates how it works.
A new model predicts how molecules will dissolve in different solvents
Solubility predictions could make it easier to design and synthesize new drugs, while minimizing the use of more hazardous solvents.
How to more efficiently study complex treatment interactions
A new approach for testing multiple treatment combinations at once could help scientists develop drugs for cancer or genetic disorders.
MIT Open Learning bootcamp supports effort to bring invention for long-term fentanyl recovery to market
The Substance Use Disorders Ventures Bootcamp ignites innovators like Evan Kharasch to turn research breakthroughs into treatments for substance use disorder.
Startup’s biosensor makes drug development and manufacturing cheaper
Protein sensor developed by alumna-founded Advanced Silicon Group can be used for research and quality control in biomanufacturing.
With AI, researchers predict the location of virtually any protein within a human cell
Trained with a joint understanding of protein and cell behavior, the model could help with diagnosing disease and developing new drugs.
Could LLMs help design our next medicines and materials?
A new method lets users ask, in plain language, for a new molecule with certain properties, and receive a detailed description of how to synthesize it.
Toward video generative models of the molecular world
Starting with a single frame in a simulation, a new system uses generative AI to emulate the dynamics of molecules, connecting static molecular structures and developing blurry pictures into videos.
MIT researchers introduce Boltz-1, a fully open-source model for predicting biomolecular structures
With models like AlphaFold3 limited to academic research, the team built an equivalent alternative, to encourage innovation more broadly.
A new framework to efficiently screen drugs
Novel method to scale phenotypic drug screening drastically reduces the number of input samples, costs, and labor required to execute a screen.
Teen uses pharmacology learned through MIT OpenCourseWare to extract and study medicinal properties of plants
Inspired by traditional medicine, 17-year-old Tomás Orellana is on a mission to identify plants that can help treat students’ health issues.
Accelerating particle size distribution estimation
MIT researchers speed up a novel AI-based estimator for medication manufacturing by 60 times.
3 Questions: What does innovation look like in the field of substance use disorder?
Hanna Adeyema and Carolina Haass-Koffler discuss the substance use disorder crisis and the future of innovation in the field.
MIT chemists synthesize plant-derived molecules that hold potential as pharmaceuticals
Large multi-ring-containing molecules known as oligocyclotryptamines have never been produced in the lab until now.