Using light to manipulate neuron excitability
A new optogenetics-based tool allows researchers to control how neurons respond to electrical input.
A new optogenetics-based tool allows researchers to control how neurons respond to electrical input.
Research reveals cells that span brain hemispheres to coordinate activity in visual processing centers, shows Alzheimer’s degrades their structure and function.
By tracking feedback during tasks, the anterior cingulate cortex notices when a new step has become necessary and signals the motor cortex to adjust.
Professor Polina Anikeeva’s innovation in the treatment of neurological disorders highlights the interdisciplinary nature of her field.
Innovative brain-wide mapping study shows that an “engram,” the ensemble of neurons encoding a memory, is widely distributed and includes regions not previously realized.
By integrating multiple sensory inputs, a loop of mutual inhibition among a small set of neurons allows worms to switch between long-lasting behavioral states.
Professors Linda Griffith and Feng Zhang along with Guillermo Ameer ScD ’99, Darrell Gaskin SM ’87, William Hahn, and Vamsi Mootha recognized for contributions to medicine, health care, and public health.
A study of mice watching movies shows our brain cells rely on a circuit of inhibitory neurons to help ensure that the same images are represented consistently.
As “visual recognition memory” emerges in the visual cortex, one circuit of inhibitory neurons supplants another, and slower neural oscillations prevail.
Frontal brain region overrides reflexive inclination of a deeper, older region when rules require.
Miniaturized device activates drugs in a small region deep within the brain.
A direct comparison of sensory and higher-order thalamic circuits reveals fundamental differences in how they control the cerebral cortex.
Norepinephrine-producing neurons in the locus coeruleus produce attention focus, impulse control via two distinct connections to prefrontal cortex.
The Feng lab has developed a next-generation optogenetic system for non-invasive stimulation of neurons.
New optogenetic technique could help restore limb movement, treat muscle tremor.