Genetics

Lifting the ban

March 10, 2009

Whitehead Institute researchers reprogrammed human skin cells from Parkinson's disease patients into an embryonic-stem-cell-like state. After removing the reprogramming genes, the scientists used these so-called induced pluripotent stem (iPS) cells to create dopamine-producing neurons, the cell type that degenerates in Parkinson's disease patients.Â To confirm that the iPS cells had become dopam...

Potential cancer-causing genes removed from engineered stem cells

Whitehead work involved reprogrammed skin cells from Parkinson's patient

March 5, 2009

Multiple genes implicated in autism

Discovery could lead to drugs targeting gene interactions

February 9, 2009

The image on the left shows a sample from a normal prostate, with organized cells lining the O-shaped ductules. Â Mice without theÂ PTENÂ gene had developed cancer, which is characterized by enlarged glands and disorganized cells clogging the ductules (middle image). Â When mTORC2 activity is blocked in mice lacking the PTENÂ gene, the prostate ductulesÂ resemble the appearance of norm...

Preventing prostate cancer the complex way

February 2, 2009

Study links genetic, environmental causes of Parkinson's

February 1, 2009

The Graybiel Lab caused Parkinson's disease in rats by depleting dopamine in the right side of the striatum, the brain region that drives the abnormal movements in the disease, leaving the left side as the control. Treating the rats with L-DOPA induced dyskinesia...

What causes motor complications of Parkinson's treatment?

MIT study identifies genes linked to key side effect; work signals new approaches

January 29, 2009

Chemistry graduate student Weerawat Runguphan, left, Sarah E. O'Connor, Latham Family Career Development Associate Professor of Chemistry, rear, and chemistry graduate student Peter Bernhardt, right, in lab where they genetically engineered periwinkle plant cells.

Chemists engineer plants to produce new compounds

Periwinkle plant cells could synthesize potential drugs

January 18, 2009

Do-it-yourself biology: Learning to build a better microbe

January 13, 2009

MIT researchers found that mice with normal DNA repair systems had more retinal degeneration upon exposure to environmental toxic agents than mice lacking a certain DNA repair system. At right, the cross section of the retina from a mouse lacking the repair system is normal. At left, mice with too much DNA repair have greatly reduced numbers of cells in the OPL (outer plexiform layer) and ONL (ou...

Too much of a good thing

Excessive DNA repair can lead to retinal degeneration

January 9, 2009

MIT researchers use this microchip to trap and fuse pairs of cells.

Getting cells to pair off

New device couples, fuses cells for stem cell research

January 4, 2009

This image shows the cell before hydrogen peroxide is added.

Nanotubes sniff out cancer agents in living cells

Chemical engineers use carbon nanotubes to monitor chemotherapy, detect toxins at the single-molecule level

December 14, 2008

Reversing the conventional DNA wisdom

Researchers find DNA is transcribed by divergent polymerases

December 4, 2008

Untangling DNA regulation

Biologists theorize role for DNA packaging in stem cell development

November 6, 2008

Human genes sing different tunes in different tissues

Biologists find almost all genes express multiple messenger RNAs

November 2, 2008

Professor of Biology Angelika Amon reports new insights into how cells divide, a process important to cancer research.

Too much of a good thing: Cells with extra chromosomes share detrimental traits

New findings could help fight cancer

October 30, 2008

MIT News | Massachusetts Institute of Technology

Browse By

Topics

Departments

Centers, Labs, & Programs

Schools

Topic