Deciphering the language of transcription factors
A new method identifies the precise binding sites of transcription factors — proteins that regulate the production of other proteins — with 10 times the accuracy of its predecessors.
Researchers identify biochemical functions for most of the human genome
New map provides a reference for interpreting function of disease-associated regions.
Turning on key enzyme blocks tumor formation
Drug-like molecule restores normal cell metabolism, preventing cancer cells from growing.
New nanoparticles shrink tumors in mice
Particles that shut off cancer genes could also allow researchers to screen potential drug targets more rapidly.
Researchers build a toolbox for synthetic biology
Engineers design new proteins that can help control novel genetic circuits in cells.
Searching genomic data faster
Biologists’ capacity for generating genomic data is increasing more rapidly than computing power. A new algorithm will help them keep up.
Genetic 911: Cells’ emergency systems revealed
Study examines how cells exploit gene sequences to cope with toxic stress.
Researchers achieve RNA interference, in a lighter package
Pared-down nucleic acid nanoparticle poses less risk of side effects, offers better targeting.
A new look at prolonged radiation exposure
MIT study suggests that at low dose-rate, radiation poses little risk to DNA.
Pinpointing how antibiotics work
Team uncovers mechanism that produces fatal DNA damage in bacteria.
Getting to the root of genetics
Manolis Kellis uses computational techniques to decipher human disease.
Study shows unified process of evolution in bacteria and sexual eukaryotes
A single gene mutation can sweep through a population, opening the door for the concept of ‘species’ in bacteria.
What lies ahead for science and science writing?
10th anniversary of MIT Graduate Program in Science Writing celebrates past, looks to future.
Eric Lander wins Dan David Prize
Broad Institute director, biology professor shares prize in the 'future' category.
Prions play key role in yeast survival and evolution
For the first time, researchers find prions in wild strains of yeast, and show they can help the organisms withstand stress.