New nanoparticles can perform gene editing in the lungs
Using these RNA-delivery particles, researchers hope to develop new treatments for cystic fibrosis and other lung diseases.
Using these RNA-delivery particles, researchers hope to develop new treatments for cystic fibrosis and other lung diseases.
Using this approach, researchers hope to deliver therapeutic RNA molecules selectively to cancer cells or other target cells.
“Single-cell profiling” is helping neuroscientists see how disease affects major brain cell types and identify common, potentially targetable pathways.
MLK Visiting Professor tries to “maximize connection time” while studying protein evolution.
Prochlorococcus, the world’s most abundant photosynthetic organism, reveals a gene-transfer mechanism that may be key to its abundance and diversity.
Gene-Wei Li investigates the rules that cells use to maintain the correct ratio of the proteins they need to survive.
Known as PASTE, the technique holds potential for treating a variety of diseases caused by faulty genes.
In people carrying APOE4, a key brain cell mismanages cholesterol needed to insulate neurons properly — another sign APOE4 contributes to disease by disrupting brain lipids.
Researchers harness new pooled, image-based screening method to probe the functions of over 5,000 essential genes in human cells.
By analyzing enzyme activity at the organism, tissue, and cellular scales, new sensors could provide new tools to clinicians and cancer researchers.
Study finds the protein MTCH2 is responsible for shuttling various other proteins into the membrane of mitochondria. The finding could have implications for cancer treatments and MTCH2-linked conditions.
A machine-learning method finds patterns of health decline in ALS, informing future clinical trial designs and mechanism discovery. The technique also extends to Alzheimer’s and Parkinson’s.
A computational analysis reveals that many repetitive sequences are shared across proteins and are similar in species from bacteria to humans.
A new model that maps developmental pathways to tumor cells may unlock the identity of cancers of unknown primary.
Alex Shalek’s technologies for single-cell RNA profiling can help dissect the cellular bases of complex diseases around the globe.