A smarter way to develop new drugs
A new artificial intelligence technique only proposes candidate molecules that can actually be produced in a lab.
An “oracle” for predicting the evolution of gene regulation
Researchers create a mathematical framework to examine the genome and detect signatures of natural selection, deciphering the evolutionary past and future of non-coding DNA.
SMART researchers discover unique lysin capable of killing multidrug-resistant bacteria
Novel lysin Abp013 has shown promising antimicrobial ability against Acinetobacter baumannii and Klebsiella pneumoniae.
Chemical synthesis yields potential antibiotic
A new strategy for producing a natural compound could also be used to generate variants with even stronger antimicrobial activity.
Measuring cancer cell state can reveal drug susceptibility
Study results also show that pancreatic tumor cells can be forced into a more susceptible state by changing their environment.
Taking some of the guesswork out of drug discovery
A deep learning model rapidly predicts the 3D shapes of drug-like molecules, which could accelerate the process of discovering new medicines.
Engineers devise a way to selectively turn on RNA therapies in human cells
A new RNA-based control switch could be used to trigger production of therapeutic proteins to treat cancer or other diseases.
Chronicles of the epic mission to deliver Covid vaccines to the world
“A Shot in the Arm,” a new book from Professor Yossi Sheffi, reveals lessons about overcoming global threats.
Chemical engineering meets cancer immunotherapy
Sachin Bhagchandani wins NCI Predoctoral to Postdoctoral Fellow Transition (F99/K00) Award.
Landmark Bio, a biomanufacturing facility co-founded by MIT, breaks ground in Watertown Arsenal
Public-private partnership aims to advance development and production of medical treatments.
Biological engineers find a new target for malaria drugs
Blocking a key enzyme could kill parasites that have evolved resistance to existing drugs.
Software to accelerate R&D
The alumni-founded startup Uncountable has developed a digital workbook to help scientists get more out of experimental data.
Speeding up clinical trials by making drug production local
Professor Tim Jamison’s company Snapdragon Chemistry helps turn the latest innovations in chemistry into impactful drugs.
Behind Covid-19 vaccine development
A machine learning model developed jointly by Janssen and MIT data scientists played a key role in the clinical trial process for the Johnson & Johnson Covid-19 vaccine.
Big data dreams for tiny technologies
MIT research combines machine learning with nanoparticle design for personalized drug delivery.