Scientists unveil more than 600 new tissue models of human cancer
Derived from patient tumor samples and available to researchers around the world, the cells will aid the development of new cancer treatments.
Single-molecule tracker illuminates workings of cancer-related proteins
Researchers can now use custom-built microscopy and nanotechnology to tag and follow the activity of individual proteins in real-time.
Self-organizing “pencil beam” laser could help scientists design brain-targeted therapies
MIT researchers leveraged a surprise discovery to devise a faster and more precise biomedical imaging technique.
Bringing AI-driven protein-design tools to biologists everywhere
Founded by Tristan Bepler PhD ’20 and former MIT professor Tim Lu PhD ’07, OpenProtein.AI offers researchers open-source models and other tools for protein engineering.
New AI model could cut the costs of developing protein drugs
MIT researchers used a large language model to optimize the genetic sequences of proteins manufactured by yeast, making production more efficient.
Using synthetic biology and AI to address global antimicrobial resistance threat
Driven by overuse and misuse of antibiotics, drug-resistant infections are on the rise, while development of new antibacterial tools has slowed.
3 Questions: Using AI to accelerate the discovery and design of therapeutic drugs
Professor James Collins discusses how collaboration has been central to his research into combining computational predictions with new experimental platforms.
Sean Luk: Addressing the urgent need for better immunotherapy
The MIT senior helps design proteins that spur the immune system to fight cancer and other diseases.
A better DNA material for genetic medicine
With its circular single-stranded DNA molecules, MIT spinout Kano Therapeutics plans to make gene and cell therapies safer and more effective.
Prognostic tool could help clinicians identify high-risk cancer patients
Using a versatile problem-solving framework, researchers show how early relapse in lymphoma patients influences their chance for survival.
MIT chemists synthesize a fungal compound that holds promise for treating brain cancer
Preliminary studies find derivatives of the compound, known as verticillin A, can kill some types of glioma cells.
MIT scientists debut a generative AI model that could create molecules addressing hard-to-treat diseases
BoltzGen generates protein binders for any biological target from scratch, expanding AI’s reach from understanding biology toward engineering it.
MIT study finds targets for a new tuberculosis vaccine
Using these antigens, researchers plan to develop vaccine candidates that they hope would stimulate a strong immune response against the world’s deadliest pathogen.
New method could improve manufacturing of gene-therapy drugs
Selective crystallization can greatly improve the purity, selectivity, and active yield of viral vector-based gene therapy drugs, MIT study finds.
Designing better, longer-lasting medicines
Adding amino acids to certain protein-based medications can improve stability and effectiveness. New MIT research demonstrates how it works.