Topic
Drug development
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Guided by AI, robotic platform automates molecule manufacture
New system could free bench chemists from time-consuming tasks, may help inspire new molecules.
August 8, 2019 -
Model predicts cognitive decline due to Alzheimer’s, up to two years out
Researchers hope the system can zero in on the right patients to enroll in clinical trials, to speed discovery of drug treatments.
August 1, 2019 -
Speeding up drug discovery for brain diseases
Whitehead Institute team finds drugs that activate a key brain gene; initial tests in cells and mice show promise for rare, untreatable neurodevelopmental disorder.
July 31, 2019 -
MIT “Russian Doll” tech lands $7.9M international award to fight brain tumors
Researchers from MIT's Koch Institute will work with teams in the UK and Europe to use nanoparticles to carry multiple drug therapies to treat glioblastoma.
July 26, 2019 -
Drug makes tumors more susceptible to chemo
Compound that knocks out a DNA repair pathway enhances cisplatin treatment and helps prevent drug-resistance.
June 6, 2019 -
Merging cell datasets, panorama style
Algorithm stitches multiple datasets into a single “panorama,” which could provide new insights for medical and biological studies.
May 6, 2019 -
New approach could accelerate efforts to catalog vast numbers of cells
Data-sampling method makes “sketches” of unwieldy biological datasets while still capturing the full diversity of cell types.
May 2, 2019 -
The fluid that feeds tumor cells
The substance that bathes tumors in the body is quite different from the medium used to grow cancer cells in the lab, biologists report.
April 16, 2019 -
Model learns how individual amino acids determine protein function
Technique could improve machine-learning tasks in protein design, drug testing, and other applications.
March 22, 2019 -
Using machine learning for medical solutions
Master’s student and Marshall Scholar Kyle Swanson uses computer science to help make drug development more efficient.
March 19, 2019 -
A new approach to drugging a difficult cancer target
Study suggests an alternative way to treat tumors that are dependent on the cancer-promoting Myc protein.
March 14, 2019 -
Tissue model reveals how RNA will act on the liver
Studies could speed the development of new treatments for liver disease.
March 5, 2019 -
A better way to measure cell survival
New test rapidly evaluates the effect of drugs and potentially toxic compounds on cells.
February 5, 2019 -
Julia Lab joins team to speed up drug approval process
Health Analytics Collective uses real-world evidence to modernize health and drug development decisions.
January 25, 2019 -
Stephen Buchwald awarded 2019 Wolf Prize for chemistry
Honor shared with John Hartwig of the University of California at Berkeley for their development of a process to improve the synthesis of large organic molecules.
January 16, 2019 -
MIT engineers repurpose wasp venom as an antibiotic drug
Altered peptides from a South American wasp’s venom can kill bacteria but are nontoxic to human cells.
December 7, 2018 -
Chemical synthesis could produce more potent antibiotics
Simple method for linking molecules could help overcome drug resistant infections.
November 5, 2018 -
Cryptographic protocol enables greater collaboration in drug discovery
Neural network that securely finds potential drugs could encourage large-scale pooling of sensitive data.
October 18, 2018 -
Computer model offers more control over protein design
New approach generates a wider variety of protein sequences optimized to bind to drug targets.
October 15, 2018 -
A new way to manufacture small batches of biopharmaceuticals on demand
System can be rapidly reconfigured to produce a variety of protein drugs.
October 1, 2018