New programmable gene editing proteins found outside of CRISPR systems
Researchers find RNA-guided enzymes are more diverse and widespread than previously believed.
Scientists harness human protein to deliver molecular medicines to cells
Made of components found in the human body, the programmable system is a step toward safer, targeted delivery of gene editing and other molecular therapeutics.
SMART researchers develop a method for rapid, accurate virus detection
Four times faster than conventional PCR methods, new RADICA approach is highly specific, sensitive, and resistant to inhibitors.
A new technique for correcting disease-causing mutations
Novel method, developed by McGovern Institute researchers, may lead to safer, more efficient gene therapies.
Accelerating the pace of engineered cell therapies, from lab to bedside
Kytopen is speeding up both discovery and delivery of engineered cell therapies with its transformative Flowfect platforms.
Using CRISPR as a research tool to develop cancer treatments
KSQ Therapeutics uses technology created at MIT to study the role of every human gene in disease biology.
An on-off switch for gene editing
New, reversible CRISPR method can control gene expression while leaving underlying DNA sequence unchanged.
A new tool to investigate bacteria behind hospital infections
Scalable CRISPRi system from SMART allows scientists to identify and tackle causes of E. faecalis-related diseases and drug resistance.
Catching cancer in the act
Using CRISPR technology, researchers are tracking the lineage of individual cancer cells as they proliferate and metastasize in real-time.
Regulating the regulators
Tiny microRNAs help destroy unwanted messenger RNAs in cells. New research finds how the body keeps them in check.
Rapid test for Covid-19 shows improved sensitivity
A CRISPR-based test developed at MIT and the Broad Institute can detect nearly as many cases as the standard Covid-19 diagnostic.
New molecular therapeutics center established at MIT's McGovern Institute
Collaborative research center funded by Lisa Yang and Hock Tan ’75 blends engineering and neuroscience to advance molecular tools for treating brain disorders.
Nature-inspired CRISPR enzymes for expansive genome editing
Applied computational biology discoveries vastly expand the range of CRISPR’s access to DNA sequences.
SHERLOCK-based one-step test provides rapid and sensitive Covid-19 detection
New CRISPR-based research tool delivers results in an hour; researchers share protocol and kits to advance research and move toward clinical validation.
CRISPR-based diagnostic chips perform thousands of tests simultaneously to detect viruses
Diagnostic platform CARMEN combines microfluidics with CRISPR-based detection technology SHERLOCK, and could one day be used for public health efforts.