MIT researchers find new immunotherapeutic targets for glioblastoma
A study profiling antigens presented on immune and tumor cells in co-culture points to new strategies for attacking a treatment-resistant and deadly brain cancer.
A new way to deliver antibodies could make treatment much easier for patients
Therapeutic antibodies packaged into microparticles could be injected with a standard syringe, avoiding the need for lengthy and often uncomfortable infusions.
Prognostic tool could help clinicians identify high-risk cancer patients
Using a versatile problem-solving framework, researchers show how early relapse in lymphoma patients influences their chance for survival.
MIT chemists synthesize a fungal compound that holds promise for treating brain cancer
Preliminary studies find derivatives of the compound, known as verticillin A, can kill some types of glioma cells.
An improved way to detach cells from culture surfaces
The approach could transform large-scale biomanufacturing by enabling automated and contamination-conscious workflows for cell therapies, tissue engineering, and regenerative medicine.
Turning on an immune pathway in tumors could lead to their destruction
MIT researchers show they can use messenger RNA to activate the pathway and trigger the immune system to attack tumors.
New nanoparticles stimulate the immune system to attack ovarian tumors
Targeted particles carrying the cytokine IL-12 can jump-start T cells, allowing them to clear tumors while avoiding side effects.
Startup’s tablets deliver cancer drugs more evenly over time
An MIT team’s technology could allow cancer drugs to be delivered more steadily into the bloodstream, to improve effectiveness and reduce side effects.
Engineered “natural killer” cells could help fight cancer
A new study identifies genetic modifications that make these immune cells, known as CAR-NK cells, more effective at destroying cancer cells.
A cysteine-rich diet may promote regeneration of the intestinal lining, study suggests
The findings may offer a new way to help heal tissue damage from radiation or chemotherapy treatment.
Inflammation jolts “sleeping” cancer cells awake, enabling them to multiply again
Chemotherapy-induced injury of organ tissue causes inflammation that awakens dormant cancer cells, which may cause new tumors to form.
“Bottlebrush” particles deliver big chemotherapy payloads directly to cancer cells
Outfitted with antibodies that guide them to the tumor site, the new nanoparticles could reduce the side effects of treatment.
Mapping cells in time and space: New tool reveals a detailed history of tumor growth
Researchers developed a tool to recreate cells’ family trees. Comparing cells’ lineages and locations within a tumor provided insights into factors shaping tumor growth.
New AI system uncovers hidden cell subtypes, boosts precision medicine
CellLENS reveals hidden patterns in cell behavior within tissues, offering deeper insights into cell heterogeneity — vital for advancing cancer immunotherapy.
MIT engineers develop electrochemical sensors for cheap, disposable diagnostics
Electrodes coated with DNA could enable inexpensive tests with a long shelf-life, which could detect many diseases and be deployed in the doctor’s office or at home.