Future science at the molecular level
Brad Pentelute and his lab compel the anthrax delivery system to deliver antibody and peptide variants into cells to treat cancer.
Study explains why certain immunotherapies don’t always work as predicted
The findings could help doctors identify cancer patients who would benefit the most from drugs called checkpoint blockade inhibitors.
A snapshot of cancer vaccine development
The Koch Institute’s Annual Symposium highlights emerging successes and challenges in the advancement of vaccines to prevent and treat cancer.
AI model can help determine where a patient’s cancer arose
Predictions from the OncoNPC model could enable doctors to choose targeted treatments for difficult-to-treat tumors.
Study finds a surprising new role for a major immune regulator
In addition to turning on genes involved in cell defense, the STING protein also acts as an ion channel, allowing it to control a wide variety of immune responses.
A wearable ultrasound scanner could detect breast cancer earlier
The new device, which can be incorporated into a bra, could allow more frequent monitoring of patients at high risk for breast cancer.
Making sense of cell fate
MIT researchers find timing and dosage of DNA-damaging drugs are key to whether a cancer cell dies or enters senescence.
A new vision for ultrasound imaging
Ultrasound research specialist and 2023 MIT Excellence Award winner Nicole Henning adapts ultrasound technology for more sensitive, less invasive imaging for disease modeling.
New sensor mimics cell membrane functions
The device detects the same molecules that cell receptors do, and may enable routine early screening for cancers and other diseases.
Vaccine delivers a boost to T cell therapy
The new strategy may enable engineered T cells to eradicate solid tumors such as glioblastoma.
Charlie Farquhar: Forger of chemical and social bonds
While developing targeted drug-delivery methods, the PhD student advocates for inclusion, belonging, and collaboration.
Exploring the links between diet and cancer
Omer Yilmaz’s work on how diet influences intestinal stem cells could lead to new ways to treat or prevent gastrointestinal cancers.
Paula Hammond wins faculty’s Killian Award for 2023-24
The chemical engineer is honored for her work designing polymers and nanomaterials with wide-ranging applications in medicine and energy.
Putting the STING into cancer immunotherapy
A cancer vaccine combining checkpoint blockade therapy and a STING-activating drug eliminates tumors and prevents recurrence in mice.
Gene-editing technique could speed up study of cancer mutations
With the new method, scientists can explore many cancer mutations whose roles are unknown, helping them develop new drugs that target those mutations.