MIT study finds targets for a new tuberculosis vaccine
Using these antigens, researchers plan to develop vaccine candidates that they hope would stimulate a strong immune response against the world’s deadliest pathogen.
Designing better, longer-lasting medicines
Adding amino acids to certain protein-based medications can improve stability and effectiveness. New MIT research demonstrates how it works.
Professor Ioannis Yannas, pioneer of regenerative medicine who invented artificial skin for the treatment of severe burns, dies at 90
A beloved member of the Department of Mechanical Engineering for nearly 60 years, Yannas helped save the lives of thousands of burn victims through his research and innovation.
In a surprising discovery, scientists find tiny loops in the genomes of dividing cells
Enabled by a new high-resolution mapping technique, the findings overturn a long-held belief that the genome loses its 3D structure when cells divide.
A new system can dial expression of synthetic genes up or down
The promoter editing system could be used to fine-tune gene therapy or to more efficiently reprogram cells for therapeutic use.
Study shows mucus contains molecules that block Salmonella infection
MIT researchers now hope to develop synthetic versions of these molecules, which could be used to treat or prevent foodborne illnesses.
This MIT spinout is taking biomolecule storage out of the freezer
Cache DNA has developed technologies that can preserve biomolecules at room temperature to make storing and transporting samples less expensive and more reliable.
New RNA tool to advance cancer and infectious disease research and treatment
Advance from SMART will help to better identify disease markers and develop targeted therapies and personalized treatment for diseases such as cancer and antibiotic-resistant infection.
Study finds cell memory can be more like a dimmer dial than an on/off switch
The findings may redefine how cell identity is established and enable the creation of more sophisticated engineered tissues.
Researchers glimpse the inner workings of protein language models
A new approach can reveal the features AI models use to predict proteins that might make good drug or vaccine targets.
Using generative AI, researchers design compounds that can kill drug-resistant bacteria
The team used two different AI approaches to design novel antibiotics, including one that showed promise against MRSA.
Ushering in a new era of suture-free tissue reconstruction for better healing
MIT spinout Tissium recently secured FDA marketing authorization of a biopolymer platform for nerve repair.
Scientists apply optical pooled CRISPR screening to identify potential new Ebola drug targets
Combining powerful imaging, perturbational screening, and machine learning, researchers uncover new human host factors that alter Ebola’s ability to infect.
MIT launches a “moonshot for menstruation science”
The Fairbairn Menstruation Science Fund will allow researchers to accelerate the understanding and treatment of often-neglected diseases that tend to be more common in women.
How to more efficiently study complex treatment interactions
A new approach for testing multiple treatment combinations at once could help scientists develop drugs for cancer or genetic disorders.