James Collins, Pablo Jarillo-Herrero, and Richard Milner have won top prizes for their work.
Engineers program human and bacterial cells to keep a record of complex molecular events.
The new system, dubbed RESCUE, allows RNA edits to be made that were not previously possible.
By introducing a gene variant associated with autism into monkeys, researchers hope to study treatment options for severe neurodevelopmental disorders.
Researchers identify and develop new CRISPR-associated transposase system for targeted integration of DNA, adding key capabilities to gene-editing technology.
CRISPR team harnesses new Cas12b enzyme for use in eukaryotic cells, adding to the CRISPR toolbox.
Enzyme can target almost half of the genome’s “ZIP codes” and could enable editing of many more disease-specific mutations.