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White line-art drawing of a brain overlaid on a horizontal-running DNA double helix, on a dark background showing ones and zeroes to represent computer code.

Alzheimer’s erodes brain cells’ control of gene expression, undermining function, cognition

Study of 3.5 million cells from more than 100 human brains finds Alzheimer’s progression — and resilience to disease — depends on preserving epigenomic stability.

September 8, 2025

Daniela Giardina stands against a colorful quilted tapestry of different faces

J-WAFS welcomes Daniela Giardina as new executive director

Succeeding founding executive director Renee Robins, Giardina will help shape and implement the goals and initiatives of MIT’s eminent water and food program.

September 4, 2025

Map of a mouse brain depicts the activity of neurons in colorful dots.

A comprehensive cellular-resolution map of brain activity

An international collaboration of neuroscientists, including MIT Professor Ila Fiete, developed a brain-wide map of decision-making at cellular resolution in mice.

September 4, 2025

Caroline Uhler stands in front of two open glass doors leading to a hallway.

3 Questions: On biology and medicine’s “data revolution”

Professor Caroline Uhler discusses her work at the Schmidt Center, thorny problems in math, and the ongoing quest to understand some of the most complex interactions in biology.

September 2, 2025

James Poitras stands in front of a large bookcase with his arms around the shoulders of Patricia Poitras and Guoping Feng

New gift expands mental illness studies at Poitras Center for Psychiatric Disorders Research

A commitment from longtime supporters Patricia and James Poitras ’63 initiates multidisciplinary efforts to understand and treat complex psychiatric disorders.

September 2, 2025

Cartoon illustration of a ribosome farmer near mitochondria selling colorful "organic" and "locally translated" proteins in cartons

Locally produced proteins help mitochondria function

Researchers developed an approach to study where proteins get made, and characterized proteins produced near mitochondria, gaining potential insights into mitochondrial function and disease.

August 27, 2025

Illustration of the inner four solar system planets orbiting the sun. None are to scale

Can large language models figure out the real world?

New test could help determine if AI systems that make accurate predictions in one area can understand it well enough to apply that ability to a different area.

August 25, 2025

Kevin Geisel in orange safety vest is placing sampling equipment on the floor in a dark subway platform.

Lincoln Laboratory reports on airborne threat mitigation for the NYC subway

Researchers studied air flow characteristics, sensor performance, and mitigation strategies within this complex subway system.

August 21, 2025

Icons of protein strands are connected to each other by lines, like a large-language model.

Researchers glimpse the inner workings of protein language models

A new approach can reveal the features AI models use to predict proteins that might make good drug or vaccine targets.

August 18, 2025

Using generative AI, researchers design compounds that can kill drug-resistant bacteria

The team used two different AI approaches to design novel antibiotics, including one that showed promise against MRSA.

August 14, 2025

“Things” and “Stuff” text. Background has four video stills showing liquids and solids going downstairs.

How the brain distinguishes oozing fluids from solid objects

A new study finds parts of the brain’s visual cortex are specialized to analyze either solid objects or flowing materials like water or sand.

July 31, 2025

Excerpt of a bar graph, with 8 bars each consisting of varying length sections of different colors

Mapping cells in time and space: New tool reveals a detailed history of tumor growth

Researchers developed a tool to recreate cells’ family trees. Comparing cells’ lineages and locations within a tumor provided insights into factors shaping tumor growth.

July 30, 2025

Kathleen Monagle and MIT President Sally Kornbluth pose together on a stage. They both hold a Collier Medal.

Staff members honored with 2025 Excellence Awards, Collier Medal, and Staff Award for Distinction in Service

The MIT community celebrates their fellow staff members’ talent and dedication to the Institute.

July 28, 2025

Merged polymer chain showing two different types of polymers

New system dramatically speeds the search for polymer materials

The platform identifies, mixes, and tests up to 700 new polymer blends a day for applications like protein stabilization, battery electrolytes, or drug-delivery materials.

July 28, 2025

Scientists apply optical pooled CRISPR screening to identify potential new Ebola drug targets

Combining powerful imaging, perturbational screening, and machine learning, researchers uncover new human host factors that alter Ebola’s ability to infect.

July 24, 2025

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