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Biochemist JoAnne Stubbe wins National Medal of Science

Nation's top science honor goes to MIT biochemist for her role in helping reveal the mechanism of enzymes involved in DNA replication and repair

September 17, 2009

In a comparison of a control to the chemical identified by the Weinberg/Lander team, called salinomycin, the tumor cells (stained dark purple in both slides) were unaffected by the control, but salinomycin killed many tumor cells (stained pink).

Taking aim at aggressive cancer cells

Researchers use novel stem-cell method to discover chemical with potency against breast tumors in mice

August 13, 2009

In mice, the loss of microRNA miR-31 allows cancer cells to spread to the lungs more easily than cancer cells with miR-31. The edge of the cancer tumors lacking miR-31 are also less defined than tumors containing cells with higher levels of miR-31.

RNA snippet suppresses spread of aggressive breast cancer

June 12, 2009

Back row left to right: Kathleen Boisvert; Philip J. Hilts, director; Dianne Finch; Sharon Weinberger; Molly Seamans; Marcin Rotkiewicz; Teresa Firmino; Karen Weintraub; Kimani Chege; Rachel Zimmerman
Front row left to right: Jonathan Fildes; Sascha Karberg; Alex Otto; Sabin Russell

11 new Knight journalism fellows arrive at MIT

September 11, 2008

Human mammary epithelial cells that undergo an epithelial-to-mesenchymal transition (EMT) in culture may grow in suspension into structures called mammospheres--a trait they share with mammary epithelial stem cells. Here, the yellow cells present surface proteins indicating that they can develop into more than one type of mammary cell.

Embryonic pathway delivers stem cell traits

May 15, 2008

Cancer researchers brief media

March 10, 2008

MIT Professor Robert Weinberg receives the Georg and Eva Klein Award from Crown Princess Victoria of Sweden at a ceremony in Stockholm on Jan. 29, 2008.

Weinberg named first recipient of Swedish science prize

January 31, 2008

Green fluorescent mesenchymal stem cells in a primary tumor. These cells may be responsible for metastasis in a significant subset of breast cancer patients.

Cancer cells enlist adult stem cells to promote metastasis

October 31, 2007

Small secondary tumors (shown in green) formed in the lungs of mice after Li Ma, a postdoctoral researcher at the Whitehead Institue for Biomedical Research, inserted human breast cancer cells into their mammary fat pads. The cancer cells, which normally don't metastasize, acquired the ability to move and invade when Ma boosted the level of a single microRNA.

Team proves role of microRNAs in spread of cancer

September 27, 2007

Grown in a newly invented culture medium, these normal human breast cells (whose membranes are stained red) form sheets.

Team finds way to create cancer stem cells

MIT achievement could aid cancer research

August 13, 2007

Center for Cancer Research receives $6 million to study tumor cell 'microenvironment'

December 1, 2006

MIT receives major grant from the Ludwig Fund to tackle metastasis

November 14, 2006

Cancer Center highlights past, present research

June 26, 2006

MIT novelist Lightman compares science, writing

April 3, 2006

Robert Weinberg wins major cancer prize

March 8, 2006

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